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Targeting resistance to radiation-immunotherapy in cold HNSCCs by modulating the Treg-dendritic cell axis.
Knitz MW, Bickett TE, Darragh LB, Oweida AJ, Bhatia S, Van Court B, Bhuvane S, Piper M, Gadwa J, Mueller AC, Nguyen D, Nangia V, Osborne DG, Bai X, Ferrara SE, Boss MK, Goodspeed A, Burchill MA, Tamburini BAJ, Chan ED, Pickering CR, Clambey ET, Karam SD. Knitz MW, et al. J Immunother Cancer. 2021 Apr;9(4):e001955. doi: 10.1136/jitc-2020-001955. J Immunother Cancer. 2021. PMID: 33883256 Free PMC article.
The effects of ephrinB2 signaling on proliferation and invasion in glioblastoma multiforme.
Bhatia S, Bukkapatnam S, Van Court B, Phan A, Oweida A, Gadwa J, Mueller AC, Piper M, Darragh L, Nguyen D, Gilani A, Knitz M, Bickett T, Green A, Venkataraman S, Vibhakar R, Cittelly D, Karam SD. Bhatia S, et al. Mol Carcinog. 2020 Sep;59(9):1064-1075. doi: 10.1002/mc.23237. Epub 2020 Jun 22. Mol Carcinog. 2020. PMID: 32567728 Free PMC article.
Induction of ADAM10 by Radiation Therapy Drives Fibrosis, Resistance, and Epithelial-to-Mesenchyal Transition in Pancreatic Cancer.
Mueller AC, Piper M, Goodspeed A, Bhuvane S, Williams JS, Bhatia S, Phan AV, Van Court B, Zolman KL, Peña B, Oweida AJ, Zakem S, Meguid C, Knitz MW, Darragh L, Bickett TE, Gadwa J, Mestroni L, Taylor MRG, Jordan KR, Dempsey P, Lucia MS, McCarter MD, Del Chiaro M, Messersmith WA, Schulick RD, Goodman KA, Gough MJ, Greene CS, Costello JC, Neto AG, Lagares D, Hansen KC, Van Bokhoven A, Karam SD. Mueller AC, et al. Among authors: knitz mw. Cancer Res. 2021 Jun 15;81(12):3255-3269. doi: 10.1158/0008-5472.CAN-20-3892. Epub 2021 Feb 1. Cancer Res. 2021. PMID: 33526513 Free PMC article.
Dichotomous effects of cellular expression of STAT3 on tumor growth of HNSCC.
Bickett TE, Knitz MW, Piper M, Oweida AJ, Gadwa J, Darragh LB, Nguyen D, Bhatia S, Bhuvane S, Phan AV, Van Court B, Corbo S, Pham T, Dent AL, Lenz L, Karam SD. Bickett TE, et al. Among authors: knitz mw. Mol Ther. 2022 Mar 2;30(3):1149-1162. doi: 10.1016/j.ymthe.2021.11.011. Epub 2021 Nov 15. Mol Ther. 2022. PMID: 34793974 Free PMC article.
Targeting Treg-Expressed STAT3 Enhances NK-Mediated Surveillance of Metastasis and Improves Therapeutic Response in Pancreatic Adenocarcinoma.
Piper M, Van Court B, Mueller A, Watanabe S, Bickett T, Bhatia S, Darragh LB, Mayeda M, Nguyen D, Gadwa J, Knitz M, Corbo S, Morgan R, Lee JJ, Dent A, Goodman K, Messersmith W, Schulick R, Del Chiaro M, Zhu Y, Kedl RM, Lenz L, Karam SD. Piper M, et al. Clin Cancer Res. 2022 Mar 1;28(5):1013-1026. doi: 10.1158/1078-0432.CCR-21-2767. Clin Cancer Res. 2022. PMID: 34862244 Free PMC article.
EphB4 and ephrinB2 act in opposition in the head and neck tumor microenvironment.
Bhatia S, Nguyen D, Darragh LB, Van Court B, Sharma J, Knitz MW, Piper M, Bukkapatnam S, Gadwa J, Bickett TE, Bhuvane S, Corbo S, Wu B, Lee Y, Fujita M, Joshi M, Heasley LE, Ferris RL, Rodriguez O, Albanese C, Kapoor M, Pasquale EB, Karam SD. Bhatia S, et al. Among authors: knitz mw. Nat Commun. 2022 Jun 20;13(1):3535. doi: 10.1038/s41467-022-31124-7. Nat Commun. 2022. PMID: 35725568 Free PMC article.
Elective nodal irradiation mitigates local and systemic immunity generated by combination radiation and immunotherapy in head and neck tumors.
Darragh LB, Gadwa J, Pham TT, Van Court B, Neupert B, Olimpo NA, Nguyen K, Nguyen D, Knitz MW, Hoen M, Corbo S, Joshi M, Zhuang Y, Amann M, Wang XJ, Dow S, Kedl RM, Samedi V, Boss MK, Karam SD. Darragh LB, et al. Among authors: knitz mw. Nat Commun. 2022 Nov 16;13(1):7015. doi: 10.1038/s41467-022-34676-w. Nat Commun. 2022. PMID: 36385142 Free PMC article.
16 results