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Kinases as targets in the treatment of solid tumors.
Giamas G, Man YL, Hirner H, Bischof J, Kramer K, Khan K, Ahmed SS, Stebbing J, Knippschild U. Giamas G, et al. Among authors: knippschild u. Cell Signal. 2010 Jul;22(7):984-1002. doi: 10.1016/j.cellsig.2010.01.011. Epub 2010 Jan 21. Cell Signal. 2010. PMID: 20096351 Review.
RITA, a novel modulator of Notch signalling, acts via nuclear export of RBP-J.
Wacker SA, Alvarado C, von Wichert G, Knippschild U, Wiedenmann J, Clauss K, Nienhaus GU, Hameister H, Baumann B, Borggrefe T, Knöchel W, Oswald F. Wacker SA, et al. Among authors: knippschild u. EMBO J. 2011 Jan 5;30(1):43-56. doi: 10.1038/emboj.2010.289. Epub 2010 Nov 23. EMBO J. 2011. PMID: 21102556 Free PMC article.
Impaired CK1 delta activity attenuates SV40-induced cellular transformation in vitro and mouse mammary carcinogenesis in vivo.
Hirner H, Günes C, Bischof J, Wolff S, Grothey A, Kühl M, Oswald F, Wegwitz F, Bösl MR, Trauzold A, Henne-Bruns D, Peifer C, Leithäuser F, Deppert W, Knippschild U. Hirner H, et al. Among authors: knippschild u. PLoS One. 2012;7(1):e29709. doi: 10.1371/journal.pone.0029709. Epub 2012 Jan 3. PLoS One. 2012. PMID: 22235331 Free PMC article.
CK1δ kinase activity is modulated by Chk1-mediated phosphorylation.
Bischof J, Randoll SJ, Süßner N, Henne-Bruns D, Pinna LA, Knippschild U. Bischof J, et al. Among authors: knippschild u. PLoS One. 2013 Jul 4;8(7):e68803. doi: 10.1371/journal.pone.0068803. Print 2013. PLoS One. 2013. PMID: 23861943 Free PMC article.
Effects of altered expression and activity levels of CK1δ and ɛ on tumor growth and survival of colorectal cancer patients.
Richter J, Ullah K, Xu P, Alscher V, Blatz A, Peifer C, Halekotte J, Leban J, Vitt D, Holzmann K, Bakulev V, Pinna LA, Henne-Bruns D, Hillenbrand A, Kornmann M, Leithäuser F, Bischof J, Knippschild U. Richter J, et al. Among authors: knippschild u. Int J Cancer. 2015 Jun 15;136(12):2799-810. doi: 10.1002/ijc.29346. Epub 2014 Dec 1. Int J Cancer. 2015. PMID: 25404202 Free article.
140 results