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Kinases as targets in the treatment of solid tumors.
Giamas G, Man YL, Hirner H, Bischof J, Kramer K, Khan K, Ahmed SS, Stebbing J, Knippschild U. Giamas G, et al. Among authors: knippschild u. Cell Signal. 2010 Jul;22(7):984-1002. doi: 10.1016/j.cellsig.2010.01.011. Epub 2010 Jan 21. Cell Signal. 2010. PMID: 20096351 Review.
Protein kinases as targets for cancer treatment.
Giamas G, Stebbing J, Vorgias CE, Knippschild U. Giamas G, et al. Among authors: knippschild u. Pharmacogenomics. 2007 Aug;8(8):1005-16. doi: 10.2217/14622416.8.8.1005. Pharmacogenomics. 2007. PMID: 17716234 Review.
Stress-activated kinases as therapeutic targets in pancreatic cancer.
Traub B, Roth A, Kornmann M, Knippschild U, Bischof J. Traub B, et al. Among authors: knippschild u. World J Gastroenterol. 2021 Aug 14;27(30):4963-4984. doi: 10.3748/wjg.v27.i30.4963. World J Gastroenterol. 2021. PMID: 34497429 Free PMC article. Review.
Anti-apoptotic and growth-stimulatory functions of CK1 delta and epsilon in ductal adenocarcinoma of the pancreas are inhibited by IC261 in vitro and in vivo.
Brockschmidt C, Hirner H, Huber N, Eismann T, Hillenbrand A, Giamas G, Radunsky B, Ammerpohl O, Bohm B, Henne-Bruns D, Kalthoff H, Leithäuser F, Trauzold A, Knippschild U. Brockschmidt C, et al. Among authors: knippschild u. Gut. 2008 Jun;57(6):799-806. doi: 10.1136/gut.2007.123695. Epub 2008 Jan 18. Gut. 2008. PMID: 18203806
Impaired CK1 delta activity attenuates SV40-induced cellular transformation in vitro and mouse mammary carcinogenesis in vivo.
Hirner H, Günes C, Bischof J, Wolff S, Grothey A, Kühl M, Oswald F, Wegwitz F, Bösl MR, Trauzold A, Henne-Bruns D, Peifer C, Leithäuser F, Deppert W, Knippschild U. Hirner H, et al. Among authors: knippschild u. PLoS One. 2012;7(1):e29709. doi: 10.1371/journal.pone.0029709. Epub 2012 Jan 3. PLoS One. 2012. PMID: 22235331 Free PMC article.
CK1δ kinase activity is modulated by Chk1-mediated phosphorylation.
Bischof J, Randoll SJ, Süßner N, Henne-Bruns D, Pinna LA, Knippschild U. Bischof J, et al. Among authors: knippschild u. PLoS One. 2013 Jul 4;8(7):e68803. doi: 10.1371/journal.pone.0068803. Print 2013. PLoS One. 2013. PMID: 23861943 Free PMC article.
Gene expression levels of Casein kinase 1 (CK1) isoforms are correlated to adiponectin levels in adipose tissue of morbid obese patients and site-specific phosphorylation mediated by CK1 influences multimerization of adiponectin.
Xu P, Fischer-Posovszky P, Bischof J, Radermacher P, Wabitsch M, Henne-Bruns D, Wolf AM, Hillenbrand A, Knippschild U. Xu P, et al. Among authors: knippschild u. Mol Cell Endocrinol. 2015 May 5;406:87-101. doi: 10.1016/j.mce.2015.02.010. Epub 2015 Feb 24. Mol Cell Endocrinol. 2015. PMID: 25724478
140 results