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The structure of the influenza A virus genome.
Dadonaite B, Gilbertson B, Knight ML, Trifkovic S, Rockman S, Laederach A, Brown LE, Fodor E, Bauer DLV. Dadonaite B, et al. Among authors: knight ml. Nat Microbiol. 2019 Nov;4(11):1781-1789. doi: 10.1038/s41564-019-0513-7. Epub 2019 Jul 22. Nat Microbiol. 2019. PMID: 31332385 Free PMC article.
Structure of an H3N2 influenza virus nucleoprotein.
Knight ML, Fan H, Bauer DLV, Grimes JM, Fodor E, Keown JR. Knight ML, et al. Acta Crystallogr F Struct Biol Commun. 2021 Jul 1;77(Pt 7):208-214. doi: 10.1107/S2053230X2100635X. Epub 2021 Jun 29. Acta Crystallogr F Struct Biol Commun. 2021. PMID: 34196611 Free PMC article.
The SARS-CoV-2 RNA polymerase is a viral RNA capping enzyme.
Walker AP, Fan H, Keown JR, Knight ML, Grimes JM, Fodor E. Walker AP, et al. Among authors: knight ml. Nucleic Acids Res. 2021 Dec 16;49(22):13019-13030. doi: 10.1093/nar/gkab1160. Nucleic Acids Res. 2021. PMID: 34850141 Free PMC article.
Correlative multi-scale cryo-imaging unveils SARS-CoV-2 assembly and egress.
Mendonça L, Howe A, Gilchrist JB, Sheng Y, Sun D, Knight ML, Zanetti-Domingues LC, Bateman B, Krebs AS, Chen L, Radecke J, Li VD, Ni T, Kounatidis I, Koronfel MA, Szynkiewicz M, Harkiolaki M, Martin-Fernandez ML, James W, Zhang P. Mendonça L, et al. Among authors: knight ml. Nat Commun. 2021 Jul 30;12(1):4629. doi: 10.1038/s41467-021-24887-y. Nat Commun. 2021. PMID: 34330917 Free PMC article.
Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2.
Huo J, Le Bas A, Ruza RR, Duyvesteyn HME, Mikolajek H, Malinauskas T, Tan TK, Rijal P, Dumoux M, Ward PN, Ren J, Zhou D, Harrison PJ, Weckener M, Clare DK, Vogirala VK, Radecke J, Moynié L, Zhao Y, Gilbert-Jaramillo J, Knight ML, Tree JA, Buttigieg KR, Coombes N, Elmore MJ, Carroll MW, Carrique L, Shah PNM, James W, Townsend AR, Stuart DI, Owens RJ, Naismith JH. Huo J, et al. Among authors: knight ml. Nat Struct Mol Biol. 2020 Sep;27(9):846-854. doi: 10.1038/s41594-020-0469-6. Epub 2020 Jul 13. Nat Struct Mol Biol. 2020. PMID: 32661423
Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient.
Zhou D, Duyvesteyn HME, Chen CP, Huang CG, Chen TH, Shih SR, Lin YC, Cheng CY, Cheng SH, Huang YC, Lin TY, Ma C, Huo J, Carrique L, Malinauskas T, Ruza RR, Shah PNM, Tan TK, Rijal P, Donat RF, Godwin K, Buttigieg KR, Tree JA, Radecke J, Paterson NG, Supasa P, Mongkolsapaya J, Screaton GR, Carroll MW, Gilbert-Jaramillo J, Knight ML, James W, Owens RJ, Naismith JH, Townsend AR, Fry EE, Zhao Y, Ren J, Stuart DI, Huang KA. Zhou D, et al. Among authors: knight ml. Nat Struct Mol Biol. 2020 Oct;27(10):950-958. doi: 10.1038/s41594-020-0480-y. Epub 2020 Jul 31. Nat Struct Mol Biol. 2020. PMID: 32737466
Inclusion of cGAMP within virus-like particle vaccines enhances their immunogenicity.
Chauveau L, Bridgeman A, Tan TK, Beveridge R, Frost JN, Rijal P, Pedroza-Pacheco I, Partridge T, Gilbert-Jaramillo J, Knight ML, Liu X, Russell RA, Borrow P, Drakesmith H, Townsend AR, Rehwinkel J. Chauveau L, et al. Among authors: knight ml. EMBO Rep. 2021 Aug 4;22(8):e52447. doi: 10.15252/embr.202152447. Epub 2021 Jun 18. EMBO Rep. 2021. PMID: 34142428 Free PMC article.
Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern.
Skelly DT, Harding AC, Gilbert-Jaramillo J, Knight ML, Longet S, Brown A, Adele S, Adland E, Brown H; Medawar Laboratory Team; Tipton T, Stafford L, Mentzer AJ, Johnson SA, Amini A; OPTIC (Oxford Protective T cell Immunology for COVID-19) Clinical Group; Tan TK, Schimanski L, Huang KA, Rijal P; PITCH (Protective Immunity T cells in Health Care Worker) Study Group; C-MORE/PHOSP-C Group; Frater J, Goulder P, Conlon CP, Jeffery K, Dold C, Pollard AJ, Sigal A, de Oliveira T, Townsend AR, Klenerman P, Dunachie SJ, Barnes E, Carroll MW, James WS. Skelly DT, et al. Among authors: knight ml. Nat Commun. 2021 Aug 17;12(1):5061. doi: 10.1038/s41467-021-25167-5. Nat Commun. 2021. PMID: 34404775 Free PMC article.
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