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Fibroblast senescence in the pathology of idiopathic pulmonary fibrosis.
Waters DW, Blokland KEC, Pathinayake PS, Burgess JK, Mutsaers SE, Prele CM, Schuliga M, Grainge CL, Knight DA. Waters DW, et al. Among authors: knight da. Am J Physiol Lung Cell Mol Physiol. 2018 Aug 1;315(2):L162-L172. doi: 10.1152/ajplung.00037.2018. Epub 2018 Apr 26. Am J Physiol Lung Cell Mol Physiol. 2018. PMID: 29696986 Free PMC article. Review.
Self DNA perpetuates IPF lung fibroblast senescence in a cGAS-dependent manner.
Schuliga M, Read J, Blokland KEC, Waters DW, Burgess J, Prêle C, Mutsaers SE, Jaffar J, Westall G, Reid A, James A, Grainge C, Knight DA. Schuliga M, et al. Among authors: knight da. Clin Sci (Lond). 2020 Apr 17;134(7):889-905. doi: 10.1042/CS20191160. Clin Sci (Lond). 2020. PMID: 32219338
A cGAS-dependent response links DNA damage and senescence in alveolar epithelial cells: a potential drug target in IPF.
Schuliga M, Kanwal A, Read J, Blokland KEC, Burgess JK, Prêle CM, Mutsaers SE, Grainge C, Thomson C, James A, Bartlett NW, Knight DA. Schuliga M, et al. Among authors: knight da. Am J Physiol Lung Cell Mol Physiol. 2021 Nov 1;321(5):L859-L871. doi: 10.1152/ajplung.00574.2020. Epub 2021 Sep 15. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 34524912 Free article.
Mitochondrial dysfunction contributes to the senescent phenotype of IPF lung fibroblasts.
Schuliga M, Pechkovsky DV, Read J, Waters DW, Blokland KEC, Reid AT, Hogaboam CM, Khalil N, Burgess JK, Prêle CM, Mutsaers SE, Jaffar J, Westall G, Grainge C, Knight DA. Schuliga M, et al. Among authors: knight da. J Cell Mol Med. 2018 Dec;22(12):5847-5861. doi: 10.1111/jcmm.13855. Epub 2018 Sep 26. J Cell Mol Med. 2018. PMID: 30255990 Free PMC article.
STAT3 Regulates the Onset of Oxidant-induced Senescence in Lung Fibroblasts.
Waters DW, Blokland KEC, Pathinayake PS, Wei L, Schuliga M, Jaffar J, Westall GP, Hansbro PM, Prele CM, Mutsaers SE, Bartlett NW, Burgess JK, Grainge CL, Knight DA. Waters DW, et al. Among authors: knight da. Am J Respir Cell Mol Biol. 2019 Jul;61(1):61-73. doi: 10.1165/rcmb.2018-0328OC. Am J Respir Cell Mol Biol. 2019. PMID: 30608861
Fibulin-1c regulates transforming growth factor-β activation in pulmonary tissue fibrosis.
Liu G, Cooley MA, Jarnicki AG, Borghuis T, Nair PM, Tjin G, Hsu AC, Haw TJ, Fricker M, Harrison CL, Jones B, Hansbro NG, Wark PA, Horvat JC, Argraves WS, Oliver BG, Knight DA, Burgess JK, Hansbro PM. Liu G, et al. Among authors: knight da. JCI Insight. 2019 Jul 25;5(16):e124529. doi: 10.1172/jci.insight.124529. JCI Insight. 2019. PMID: 31343988 Free PMC article.
264 results