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Role for NLRP3 Inflammasome-mediated, IL-1β-Dependent Responses in Severe, Steroid-Resistant Asthma.
Kim RY, Pinkerton JW, Essilfie AT, Robertson AAB, Baines KJ, Brown AC, Mayall JR, Ali MK, Starkey MR, Hansbro NG, Hirota JA, Wood LG, Simpson JL, Knight DA, Wark PA, Gibson PG, O'Neill LAJ, Cooper MA, Horvat JC, Hansbro PM. Kim RY, et al. Among authors: knight da. Am J Respir Crit Care Med. 2017 Aug 1;196(3):283-297. doi: 10.1164/rccm.201609-1830OC. Am J Respir Crit Care Med. 2017. PMID: 28252317
The nucleotide-binding domain, leucine-rich repeat protein 3 inflammasome/IL-1 receptor I axis mediates innate, but not adaptive, immune responses after exposure to particulate matter under 10 μm.
Hirota JA, Gold MJ, Hiebert PR, Parkinson LG, Wee T, Smith D, Hansbro PM, Carlsten C, VanEeden S, Sin DD, McNagny KM, Knight DA. Hirota JA, et al. Among authors: knight da. Am J Respir Cell Mol Biol. 2015 Jan;52(1):96-105. doi: 10.1165/rcmb.2014-0158OC. Am J Respir Cell Mol Biol. 2015. PMID: 24988285
Inflammasomes in the lung.
Pinkerton JW, Kim RY, Robertson AAB, Hirota JA, Wood LG, Knight DA, Cooper MA, O'Neill LAJ, Horvat JC, Hansbro PM. Pinkerton JW, et al. Among authors: knight da. Mol Immunol. 2017 Jun;86:44-55. doi: 10.1016/j.molimm.2017.01.014. Epub 2017 Jan 24. Mol Immunol. 2017. PMID: 28129896 Review.
Elucidating novel disease mechanisms in severe asthma.
Kim RY, Rae B, Neal R, Donovan C, Pinkerton J, Balachandran L, Starkey MR, Knight DA, Horvat JC, Hansbro PM. Kim RY, et al. Among authors: knight da. Clin Transl Immunology. 2016 Jul 15;5(7):e91. doi: 10.1038/cti.2016.37. eCollection 2016 Jul. Clin Transl Immunology. 2016. PMID: 27525064 Free PMC article. Review.
The genetic and epigenetic landscapes of the epithelium in asthma.
Moheimani F, Hsu AC, Reid AT, Williams T, Kicic A, Stick SM, Hansbro PM, Wark PA, Knight DA. Moheimani F, et al. Among authors: knight da. Respir Res. 2016 Sep 22;17(1):119. doi: 10.1186/s12931-016-0434-4. Respir Res. 2016. PMID: 27658857 Free PMC article. Review.
264 results