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The autism susceptibility kinase, TAOK2, phosphorylates eEF2 and modulates translation.
Henis M, Rücker T, Scharrenberg R, Richter M, Baltussen L, Hong S, Meka DP, Schwanke B, Neelagandan N, Daaboul D, Murtaza N, Krisp C, Harder S, Schlüter H, Kneussel M, Hermans-Borgmeyer I, de Wit J, Singh KK, Duncan KE, de Anda FC. Henis M, et al. Among authors: kneussel m. Sci Adv. 2024 Apr 12;10(15):eadf7001. doi: 10.1126/sciadv.adf7001. Epub 2024 Apr 12. Sci Adv. 2024. PMID: 38608030 Free PMC article.
The Microtubule Severing Protein Katanin Regulates Proliferation of Neuronal Progenitors in Embryonic and Adult Neurogenesis.
Lombino FL, Muhia M, Lopez-Rojas J, Brill MS, Thies E, Ruschkies L, Lutz D, Richter M, Hausrat TJ, Lopes AT, McNally FJ, Hermans-Borgmeyer I, Dunleavy JEM, Hoffmeister-Ullerich S, Frotscher M, Misgeld T, Kreutz MR, de Anda FC, Kneussel M. Lombino FL, et al. Among authors: kneussel m. Sci Rep. 2019 Nov 4;9(1):15940. doi: 10.1038/s41598-019-52367-3. Sci Rep. 2019. PMID: 31685876 Free PMC article.
Spastin depletion increases tubulin polyglutamylation and impairs kinesin-mediated neuronal transport, leading to working and associative memory deficits.
Lopes AT, Hausrat TJ, Heisler FF, Gromova KV, Lombino FL, Fischer T, Ruschkies L, Breiden P, Thies E, Hermans-Borgmeyer I, Schweizer M, Schwarz JR, Lohr C, Kneussel M. Lopes AT, et al. Among authors: kneussel m. PLoS Biol. 2020 Aug 31;18(8):e3000820. doi: 10.1371/journal.pbio.3000820. eCollection 2020 Aug. PLoS Biol. 2020. PMID: 32866173 Free PMC article.
The Kinesin KIF21B Regulates Microtubule Dynamics and Is Essential for Neuronal Morphology, Synapse Function, and Learning and Memory.
Muhia M, Thies E, Labonté D, Ghiretti AE, Gromova KV, Xompero F, Lappe-Siefke C, Hermans-Borgmeyer I, Kuhl D, Schweizer M, Ohana O, Schwarz JR, Holzbaur ELF, Kneussel M. Muhia M, et al. Among authors: kneussel m. Cell Rep. 2016 May 3;15(5):968-977. doi: 10.1016/j.celrep.2016.03.086. Epub 2016 Apr 21. Cell Rep. 2016. PMID: 27117409 Free PMC article.
107 results