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Angiopoietin-like 3-derivative LNA043 for cartilage regeneration in osteoarthritis: a randomized phase 1 trial.
Gerwin N, Scotti C, Halleux C, Fornaro M, Elliott J, Zhang Y, Johnson K, Shi J, Walter S, Li Y, Jacobi C, Laplanche N, Belaud M, Paul J, Glowacki G, Peters T, Wharton KA Jr, Vostiar I, Polus F, Kramer I, Guth S, Seroutou A, Choudhury S, Laurent D, Gimbel J, Goldhahn J, Schieker M, Brachat S, Roubenoff R, Kneissel M. Gerwin N, et al. Among authors: kneissel m. Nat Med. 2022 Dec;28(12):2633-2645. doi: 10.1038/s41591-022-02059-9. Epub 2022 Dec 1. Nat Med. 2022. PMID: 36456835 Free PMC article. Clinical Trial.
Does osteocytic SOST suppression mediate PTH bone anabolism?
Kramer I, Keller H, Leupin O, Kneissel M. Kramer I, et al. Among authors: kneissel m. Trends Endocrinol Metab. 2010 Apr;21(4):237-44. doi: 10.1016/j.tem.2009.12.002. Epub 2010 Jan 13. Trends Endocrinol Metab. 2010. PMID: 20074973 Review.
Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis.
Kramer I, Halleux C, Keller H, Pegurri M, Gooi JH, Weber PB, Feng JQ, Bonewald LF, Kneissel M. Kramer I, et al. Among authors: kneissel m. Mol Cell Biol. 2010 Jun;30(12):3071-85. doi: 10.1128/MCB.01428-09. Epub 2010 Apr 19. Mol Cell Biol. 2010. PMID: 20404086 Free PMC article.
Bone overgrowth-associated mutations in the LRP4 gene impair sclerostin facilitator function.
Leupin O, Piters E, Halleux C, Hu S, Kramer I, Morvan F, Bouwmeester T, Schirle M, Bueno-Lozano M, Fuentes FJ, Itin PH, Boudin E, de Freitas F, Jennes K, Brannetti B, Charara N, Ebersbach H, Geisse S, Lu CX, Bauer A, Van Hul W, Kneissel M. Leupin O, et al. Among authors: kneissel m. J Biol Chem. 2011 Jun 3;286(22):19489-500. doi: 10.1074/jbc.M110.190330. Epub 2011 Apr 6. J Biol Chem. 2011. PMID: 21471202 Free PMC article.
Mef2c deletion in osteocytes results in increased bone mass.
Kramer I, Baertschi S, Halleux C, Keller H, Kneissel M. Kramer I, et al. Among authors: kneissel m. J Bone Miner Res. 2012 Feb;27(2):360-73. doi: 10.1002/jbmr.1492. J Bone Miner Res. 2012. PMID: 22161640 Free article.
73 results