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Page 1
Spray drying siRNA-lipid nanoparticles for dry powder pulmonary delivery.
Zimmermann CM, Baldassi D, Chan K, Adams NBP, Neumann A, Porras-Gonzalez DL, Wei X, Kneidinger N, Stoleriu MG, Burgstaller G, Witzigmann D, Luciani P, Merkel OM. Zimmermann CM, et al. Among authors: kneidinger n. J Control Release. 2022 Nov;351:137-150. doi: 10.1016/j.jconrel.2022.09.021. Epub 2022 Sep 22. J Control Release. 2022. PMID: 36126785 Free PMC article.
Precision 3D-Printed Cell Scaffolds Mimicking Native Tissue Composition and Mechanics.
Erben A, Hörning M, Hartmann B, Becke T, Eisler SA, Southan A, Cranz S, Hayden O, Kneidinger N, Königshoff M, Lindner M, Tovar GEM, Burgstaller G, Clausen-Schaumann H, Sudhop S, Heymann M. Erben A, et al. Among authors: kneidinger n. Adv Healthc Mater. 2020 Dec;9(24):e2000918. doi: 10.1002/adhm.202000918. Epub 2020 Oct 7. Adv Healthc Mater. 2020. PMID: 33025765
Targeting genomic SARS-CoV-2 RNA with siRNAs allows efficient inhibition of viral replication and spread.
Ambike S, Cheng CC, Feuerherd M, Velkov S, Baldassi D, Afridi SQ, Porras-Gonzalez D, Wei X, Hagen P, Kneidinger N, Stoleriu MG, Grass V, Burgstaller G, Pichlmair A, Merkel OM, Ko C, Michler T. Ambike S, et al. Among authors: kneidinger n. Nucleic Acids Res. 2022 Jan 11;50(1):333-349. doi: 10.1093/nar/gkab1248. Nucleic Acids Res. 2022. PMID: 34928377 Free PMC article.
Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics.
Gerckens M, Schorpp K, Pelizza F, Wögrath M, Reichau K, Ma H, Dworsky AM, Sengupta A, Stoleriu MG, Heinzelmann K, Merl-Pham J, Irmler M, Alsafadi HN, Trenkenschuh E, Sarnova L, Jirouskova M, Frieß W, Hauck SM, Beckers J, Kneidinger N, Behr J, Hilgendorff A, Hadian K, Lindner M, Königshoff M, Eickelberg O, Gregor M, Plettenburg O, Yildirim AÖ, Burgstaller G. Gerckens M, et al. Among authors: kneidinger n. Sci Adv. 2021 Dec 24;7(52):eabb3673. doi: 10.1126/sciadv.abb3673. Epub 2021 Dec 22. Sci Adv. 2021. PMID: 34936468 Free PMC article.
Inhibition of SARS-CoV-2 replication in the lung with siRNA/VIPER polyplexes.
Baldassi D, Ambike S, Feuerherd M, Cheng CC, Peeler DJ, Feldmann DP, Porras-Gonzalez DL, Wei X, Keller LA, Kneidinger N, Stoleriu MG, Popp A, Burgstaller G, Pun SH, Michler T, Merkel OM. Baldassi D, et al. Among authors: kneidinger n. J Control Release. 2022 May;345:661-674. doi: 10.1016/j.jconrel.2022.03.051. Epub 2022 Mar 29. J Control Release. 2022. PMID: 35364120 Free PMC article.
Ex vivo tissue perturbations coupled to single-cell RNA-seq reveal multilineage cell circuit dynamics in human lung fibrogenesis.
Lang NJ, Gote-Schniering J, Porras-Gonzalez D, Yang L, De Sadeleer LJ, Jentzsch RC, Shitov VA, Zhou S, Ansari M, Agami A, Mayr CH, Hooshiar Kashani B, Chen Y, Heumos L, Pestoni JC, Molnar ES, Geeraerts E, Anquetil V, Saniere L, Wögrath M, Gerckens M, Lehmann M, Yildirim AÖ, Hatz R, Kneidinger N, Behr J, Wuyts WA, Stoleriu MG, Luecken MD, Theis FJ, Burgstaller G, Schiller HB. Lang NJ, et al. Among authors: kneidinger n. Sci Transl Med. 2023 Dec 6;15(725):eadh0908. doi: 10.1126/scitranslmed.adh0908. Epub 2023 Dec 6. Sci Transl Med. 2023. PMID: 38055803
Sfrp1 inhibits lung fibroblast invasion during transition to injury-induced myofibroblasts.
Mayr CH, Sengupta A, Asgharpour S, Ansari M, Pestoni JC, Ogar P, Angelidis I, Liontos A, Rodriguez-Castillo JA, Lang NJ, Strunz M, Porras-Gonzalez D, Gerckens M, De Sadeleer LJ, Oehrle B, Viteri-Alvarez V, Fernandez IE, Tallquist M, Irmler M, Beckers J, Eickelberg O, Stoleriu GM, Behr J, Kneidinger N, Wuyts WA, Wasnick RM, Yildirim AÖ, Ahlbrecht K, Morty RE, Samakovlis C, Theis FJ, Burgstaller G, Schiller HB. Mayr CH, et al. Among authors: kneidinger n. Eur Respir J. 2024 Feb 8;63(2):2301326. doi: 10.1183/13993003.01326-2023. Print 2024 Feb. Eur Respir J. 2024. PMID: 38212077 Free PMC article.
FK506-Binding Protein 11 Is a Novel Plasma Cell-Specific Antibody Folding Catalyst with Increased Expression in Idiopathic Pulmonary Fibrosis.
Preisendörfer S, Ishikawa Y, Hennen E, Winklmeier S, Schupp JC, Knüppel L, Fernandez IE, Binzenhöfer L, Flatley A, Juan-Guardela BM, Ruppert C, Guenther A, Frankenberger M, Hatz RA, Kneidinger N, Behr J, Feederle R, Schepers A, Hilgendorff A, Kaminski N, Meinl E, Bächinger HP, Eickelberg O, Staab-Weijnitz CA. Preisendörfer S, et al. Among authors: kneidinger n. Cells. 2022 Apr 14;11(8):1341. doi: 10.3390/cells11081341. Cells. 2022. PMID: 35456020 Free PMC article.
130 results