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Nrf2 activation reprograms macrophage intermediary metabolism and suppresses the type I interferon response.
Ryan DG, Knatko EV, Casey AM, Hukelmann JL, Dayalan Naidu S, Brenes AJ, Ekkunagul T, Baker C, Higgins M, Tronci L, Nikitopolou E, Honda T, Hartley RC, O'Neill LAJ, Frezza C, Lamond AI, Abramov AY, Arthur JSC, Cantrell DA, Murphy MP, Dinkova-Kostova AT. Ryan DG, et al. Among authors: knatko ev. iScience. 2022 Jan 30;25(2):103827. doi: 10.1016/j.isci.2022.103827. eCollection 2022 Feb 18. iScience. 2022. PMID: 35198887 Free PMC article.
Synthesis of (13) C2 (15) N2 -labeled anti-inflammatory and cytoprotective tricyclic bis(cyanoenone) ([(13) C2 (15) N2 ]-TBE-31) as an internal standard for quantification by stable isotope dilution LC-MS method.
Zheng S, Huang JT, Knatko EV, Sharp S, Higgins M, Ojima I, Dinkova-Kostova AT, Honda T. Zheng S, et al. Among authors: knatko ev. J Labelled Comp Radiopharm. 2014 Aug;57(10):606-10. doi: 10.1002/jlcr.3230. Epub 2014 Sep 5. J Labelled Comp Radiopharm. 2014. PMID: 25196444
Nrf2 Activation Protects against Solar-Simulated Ultraviolet Radiation in Mice and Humans.
Knatko EV, Ibbotson SH, Zhang Y, Higgins M, Fahey JW, Talalay P, Dawe RS, Ferguson J, Huang JT, Clarke R, Zheng S, Saito A, Kalra S, Benedict AL, Honda T, Proby CM, Dinkova-Kostova AT. Knatko EV, et al. Cancer Prev Res (Phila). 2015 Jun;8(6):475-86. doi: 10.1158/1940-6207.CAPR-14-0362. Epub 2015 Mar 24. Cancer Prev Res (Phila). 2015. PMID: 25804610 Free PMC article.
Pharmacokinetics and pharmacodynamics of orally administered acetylenic tricyclic bis(cyanoenone), a highly potent Nrf2 activator with a reversible covalent mode of action.
Kostov RV, Knatko EV, McLaughlin LA, Henderson CJ, Zheng S, Huang JT, Honda T, Dinkova-Kostova AT. Kostov RV, et al. Among authors: knatko ev. Biochem Biophys Res Commun. 2015 Sep 25;465(3):402-7. doi: 10.1016/j.bbrc.2015.08.016. Epub 2015 Aug 8. Biochem Biophys Res Commun. 2015. PMID: 26265043 Free PMC article.
Activation of Nrf2 Signaling Augments Vesicular Stomatitis Virus Oncolysis via Autophagy-Driven Suppression of Antiviral Immunity.
Olagnier D, Lababidi RR, Hadj SB, Sze A, Liu Y, Naidu SD, Ferrari M, Jiang Y, Chiang C, Beljanski V, Goulet ML, Knatko EV, Dinkova-Kostova AT, Hiscott J, Lin R. Olagnier D, et al. Among authors: knatko ev. Mol Ther. 2017 Aug 2;25(8):1900-1916. doi: 10.1016/j.ymthe.2017.04.022. Epub 2017 May 17. Mol Ther. 2017. PMID: 28527723 Free PMC article.
22 results