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Procalcitonin is expressed in osteoblasts and limits bone resorption through inhibition of macrophage migration during intermittent PTH treatment.
Baranowsky A, Jahn D, Jiang S, Yorgan T, Ludewig P, Appelt J, Albrecht KK, Otto E, Knapstein P, Donat A, Winneberger J, Rosenthal L, Köhli P, Erdmann C, Fuchs M, Frosch KH, Tsitsilonis S, Amling M, Schinke T, Keller J. Baranowsky A, et al. Among authors: knapstein p. Bone Res. 2022 Jan 27;10(1):9. doi: 10.1038/s41413-021-00172-y. Bone Res. 2022. PMID: 35087025 Free PMC article.
Systemic calcitonin gene-related peptide receptor antagonism decreases survival in a porcine model of polymicrobial sepsis: blinded randomised controlled trial.
Messerer DAC, Datzmann T, Baranowsky A, Peschel L, Hoffmann A, Gröger M, Amling M, Wepler M, Nussbaum BL, Jiang S, Knapstein P, Donat A, Calzia E, Radermacher P, Keller J. Messerer DAC, et al. Among authors: knapstein p. Br J Anaesth. 2022 May;128(5):864-873. doi: 10.1016/j.bja.2021.11.042. Epub 2022 Feb 4. Br J Anaesth. 2022. PMID: 35131096 Free article. Clinical Trial.
Increased β2-adrenergic signaling promotes fracture healing through callus neovascularization in mice.
Jahn D, Knapstein PR, Otto E, Köhli P, Sevecke J, Graef F, Graffmann C, Fuchs M, Jiang S, Rickert M, Erdmann C, Appelt J, Revend L, Küttner Q, Witte J, Rahmani A, Duda G, Xie W, Donat A, Schinke T, Ivanov A, Tchouto MN, Beule D, Frosch KH, Baranowsky A, Tsitsilonis S, Keller J. Jahn D, et al. Among authors: knapstein pr. Sci Transl Med. 2024 Apr 17;16(743):eadk9129. doi: 10.1126/scitranslmed.adk9129. Epub 2024 Apr 17. Sci Transl Med. 2024. PMID: 38630849
Tranexamic Acid Attenuates the Progression of Posttraumatic Osteoarthritis in Mice.
Xie W, Jiang S, Donat A, Knapstein PR, Albertsen LC, Kokot JL, Erdmann C, Rolvien T, Frosch KH, Baranowsky A, Keller J. Xie W, et al. Among authors: knapstein pr. Am J Sports Med. 2024 Mar;52(3):766-778. doi: 10.1177/03635465231220855. Epub 2024 Feb 2. Am J Sports Med. 2024. PMID: 38305280 Free PMC article.
Increased beta2-adrenergic signaling is a targetable stimulus essential for bone healing by promoting callus neovascularization.
Jahn D, Knapstein PR, Otto E, Köhli P, Sevecke J, Graef F, Graffmann C, Fuchs M, Jiang S, Rickert M, Erdmann C, Appelt J, Revend L, Küttner Q, Witte J, Rahmani A, Duda G, Xie W, Donat A, Schinke T, Ivanov A, Tchouto MN, Beule D, Frosch KH, Baranowsky A, Tsitsilonis S, Keller J. Jahn D, et al. Among authors: knapstein pr. bioRxiv [Preprint]. 2023 Jul 16:2023.07.14.548550. doi: 10.1101/2023.07.14.548550. bioRxiv. 2023. PMID: 37502964 Free PMC article. Updated. Preprint.
156 results