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DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma.
Strubel A, Münick P, Hartmann O, Chaikuad A, Dreier B, Schaefer JV, Gebel J, Osterburg C, Tuppi M, Schäfer B, Buck V, Rosenfeldt M, Knapp S, Plückthun A, Diefenbacher ME, Dötsch V. Strubel A, et al. Among authors: knapp s. Cell Death Dis. 2023 Oct 12;14(10):674. doi: 10.1038/s41419-023-06213-0. Cell Death Dis. 2023. PMID: 37828008 Free PMC article.
Structural comparison of human mammalian ste20-like kinases.
Record CJ, Chaikuad A, Rellos P, Das S, Pike AC, Fedorov O, Marsden BD, Knapp S, Lee WH. Record CJ, et al. Among authors: knapp s. PLoS One. 2010 Aug 6;5(8):e11905. doi: 10.1371/journal.pone.0011905. PLoS One. 2010. PMID: 20730082 Free PMC article.
DNA damage in oocytes induces a switch of the quality control factor TAp63α from dimer to tetramer.
Deutsch GB, Zielonka EM, Coutandin D, Weber TA, Schäfer B, Hannewald J, Luh LM, Durst FG, Ibrahim M, Hoffmann J, Niesen FH, Sentürk A, Kunkel H, Brutschy B, Schleiff E, Knapp S, Acker-Palmer A, Grez M, McKeon F, Dötsch V. Deutsch GB, et al. Among authors: knapp s. Cell. 2011 Feb 18;144(4):566-76. doi: 10.1016/j.cell.2011.01.013. Cell. 2011. PMID: 21335238 Free PMC article.
The ins and outs of selective kinase inhibitor development.
Müller S, Chaikuad A, Gray NS, Knapp S. Müller S, et al. Among authors: knapp s. Nat Chem Biol. 2015 Nov;11(11):818-21. doi: 10.1038/nchembio.1938. Nat Chem Biol. 2015. PMID: 26485069 No abstract available.
Co-crystal structures of the protein kinase haspin with bisubstrate inhibitors.
Lavogina D, Kestav K, Chaikuad A, Heroven C, Knapp S, Uri A. Lavogina D, et al. Among authors: knapp s. Acta Crystallogr F Struct Biol Commun. 2016 May;72(Pt 5):339-45. doi: 10.1107/S2053230X16004611. Epub 2016 Apr 22. Acta Crystallogr F Struct Biol Commun. 2016. PMID: 27139824 Free PMC article.
Mechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerization.
Gebel J, Luh LM, Coutandin D, Osterburg C, Löhr F, Schäfer B, Frombach AS, Sumyk M, Buchner L, Krojer T, Salah E, Mathea S, Güntert P, Knapp S, Dötsch V. Gebel J, et al. Among authors: knapp s. Cell Death Differ. 2016 Dec;23(12):1930-1940. doi: 10.1038/cdd.2016.83. Epub 2016 Oct 7. Cell Death Differ. 2016. PMID: 27716744 Free PMC article.
1,279 results