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Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis.
He D, Feng H, Sundberg B, Yang J, Powers J, Christian AH, Wilkinson JE, Monnin C, Avizonis D, Thomas CJ, Friedman RA, Kluger MD, Hollingsworth MA, Grandgenett PM, Klute KA, Toste FD, Chang CJ, Chio IIC. He D, et al. Among authors: klute ka. Mol Cell. 2022 Aug 18;82(16):3045-3060.e11. doi: 10.1016/j.molcel.2022.06.005. Epub 2022 Jun 24. Mol Cell. 2022. PMID: 35752173 Free PMC article.
Antiemetic Guidelines: Not Just for the HEC of It.
Klute KA. Klute KA. J Natl Compr Canc Netw. 2020 Jun;18(6):791-792. doi: 10.6004/jnccn.2020.7589. J Natl Compr Canc Netw. 2020. PMID: 32764185 No abstract available.
Cobimetinib Plus Vemurafenib in Patients With Colorectal Cancer With BRAF Mutations: Results From the Targeted Agent and Profiling Utilization Registry (TAPUR) Study.
Klute KA, Rothe M, Garrett-Mayer E, Mangat PK, Nazemzadeh R, Yost KJ, Duvivier HL, Ahn ER, Cannon TL, Alese OB, Krauss JC, Thota R, Calfa CJ, Denlinger CS, O'Lone R, Halabi S, Grantham GN, Schilsky RL. Klute KA, et al. JCO Precis Oncol. 2022 Nov;6:e2200191. doi: 10.1200/PO.22.00191. JCO Precis Oncol. 2022. PMID: 36409971
SIRT1-NOX4 signaling axis regulates cancer cachexia.
Dasgupta A, Shukla SK, Vernucci E, King RJ, Abrego J, Mulder SE, Mullen NJ, Graves G, Buettner K, Thakur R, Murthy D, Attri KS, Wang D, Chaika NV, Pacheco CG, Rai I, Engle DD, Grandgenett PM, Punsoni M, Reames BN, Teoh-Fitzgerald M, Oberley-Deegan R, Yu F, Klute KA, Hollingsworth MA, Zimmerman MC, Mehla K, Sadoshima J, Tuveson DA, Singh PK. Dasgupta A, et al. Among authors: klute ka. J Exp Med. 2020 Jul 6;217(7):e20190745. doi: 10.1084/jem.20190745. J Exp Med. 2020. PMID: 32441762 Free PMC article.
Disruption of FDPS/Rac1 axis radiosensitizes pancreatic ductal adenocarcinoma by attenuating DNA damage response and immunosuppressive signalling.
Seshacharyulu P, Halder S, Nimmakayala R, Rachagani S, Chaudhary S, Atri P, Chirravuri-Venkata R, Ouellette MM, Carmicheal J, Gautam SK, Vengoji R, Wang S, Li S, Smith L, Talmon GA, Klute K, Ly Q, Reames BN, Grem JL, Berim L, Padussis JC, Kaur S, Kumar S, Ponnusamy MP, Jain M, Lin C, Batra SK. Seshacharyulu P, et al. EBioMedicine. 2022 Jan;75:103772. doi: 10.1016/j.ebiom.2021.103772. Epub 2021 Dec 28. EBioMedicine. 2022. PMID: 34971971 Free PMC article.
Pancreatic Adenocarcinoma, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology.
Tempero MA, Malafa MP, Al-Hawary M, Behrman SW, Benson AB, Cardin DB, Chiorean EG, Chung V, Czito B, Del Chiaro M, Dillhoff M, Donahue TR, Dotan E, Ferrone CR, Fountzilas C, Hardacre J, Hawkins WG, Klute K, Ko AH, Kunstman JW, LoConte N, Lowy AM, Moravek C, Nakakura EK, Narang AK, Obando J, Polanco PM, Reddy S, Reyngold M, Scaife C, Shen J, Vollmer C, Wolff RA, Wolpin BM, Lynn B, George GV. Tempero MA, et al. J Natl Compr Canc Netw. 2021 Apr 1;19(4):439-457. doi: 10.6004/jnccn.2021.0017. J Natl Compr Canc Netw. 2021. PMID: 33845462
34 results