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Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride-rich lipoprotein metabolism.
Deprince A, Hennuyer N, Kooijman S, Pronk ACM, Baugé E, Lienard V, Verrijken A, Dirinck E, Vonghia L, Woitrain E, Kloosterhuis NJ, Marez E, Jacquemain P, Wolters JC, Lalloyer F, Eberlé D, Quemener S, Vallez E, Tailleux A, Kouach M, Goossens JF, Raverdy V, Derudas B, Kuivenhoven JA, Croyal M, van de Sluis B, Francque S, Pattou F, Rensen PCN, Staels B, Haas JT. Deprince A, et al. Among authors: kloosterhuis nj. Hepatology. 2023 Apr 1;77(4):1287-1302. doi: 10.1002/hep.32631. Epub 2022 Jul 15. Hepatology. 2023. PMID: 35735979 Free PMC article.
Tumor necrosis factor receptor 1 gain-of-function mutation aggravates nonalcoholic fatty liver disease but does not cause insulin resistance in a murine model.
Aparicio-Vergara M, Hommelberg PP, Schreurs M, Gruben N, Stienstra R, Shiri-Sverdlov R, Kloosterhuis NJ, de Bruin A, van de Sluis B, Koonen DP, Hofker MH. Aparicio-Vergara M, et al. Among authors: kloosterhuis nj. Hepatology. 2013 Feb;57(2):566-76. doi: 10.1002/hep.26046. Epub 2013 Jan 10. Hepatology. 2013. PMID: 22941955
Chemokine-like receptor 1 deficiency does not affect the development of insulin resistance and nonalcoholic fatty liver disease in mice.
Gruben N, Aparicio Vergara M, Kloosterhuis NJ, van der Molen H, Stoelwinder S, Youssef S, de Bruin A, Delsing DJ, Kuivenhoven JA, van de Sluis B, Hofker MH, Koonen DP. Gruben N, et al. Among authors: kloosterhuis nj. PLoS One. 2014 Apr 29;9(4):e96345. doi: 10.1371/journal.pone.0096345. eCollection 2014. PLoS One. 2014. PMID: 24781986 Free PMC article.
Cholesterol-induced hepatic inflammation does not underlie the predisposition to insulin resistance in dyslipidemic female LDL receptor knockout mice.
Gruben N, Funke A, Kloosterhuis NJ, Schreurs M, Sheedfar F, Havinga R, Houten SM, Shiri-Sverdlov R, van de Sluis B, Kuivenhoven JA, Koonen DP, Hofker MH. Gruben N, et al. Among authors: kloosterhuis nj. J Diabetes Res. 2015;2015:956854. doi: 10.1155/2015/956854. Epub 2015 Feb 28. J Diabetes Res. 2015. PMID: 25815343 Free PMC article.
The COMMD Family Regulates Plasma LDL Levels and Attenuates Atherosclerosis Through Stabilizing the CCC Complex in Endosomal LDLR Trafficking.
Fedoseienko A, Wijers M, Wolters JC, Dekker D, Smit M, Huijkman N, Kloosterhuis N, Klug H, Schepers A, Willems van Dijk K, Levels JHM, Billadeau DD, Hofker MH, van Deursen J, Westerterp M, Burstein E, Kuivenhoven JA, van de Sluis B. Fedoseienko A, et al. Circ Res. 2018 Jun 8;122(12):1648-1660. doi: 10.1161/CIRCRESAHA.117.312004. Epub 2018 Mar 15. Circ Res. 2018. PMID: 29545368
The hepatic WASH complex is required for efficient plasma LDL and HDL cholesterol clearance.
Wijers M, Zanoni P, Liv N, Vos DY, Jäckstein MY, Smit M, Wilbrink S, Wolters JC, van der Veen YT, Huijkman N, Dekker D, Kloosterhuis N, van Dijk TH, Billadeau DD, Kuipers F, Klumperman J, von Eckardstein A, Kuivenhoven JA, van de Sluis B. Wijers M, et al. JCI Insight. 2019 Jun 6;4(11):e126462. doi: 10.1172/jci.insight.126462. eCollection 2019 Jun 6. JCI Insight. 2019. PMID: 31167970 Free PMC article.
A common variant in CCDC93 protects against myocardial infarction and cardiovascular mortality by regulating endosomal trafficking of low-density lipoprotein receptor.
Rimbert A, Dalila N, Wolters JC, Huijkman N, Smit M, Kloosterhuis N, Riemsma M, van der Veen Y, Singla A, van Dijk F; Biobank-Based Integrative Omics Studies Consortium; Frikke-Schmidt R, Burstein E, Tybjærg-Hansen A, van de Sluis B, Kuivenhoven JA. Rimbert A, et al. Eur Heart J. 2020 Mar 1;41(9):1040-1053. doi: 10.1093/eurheartj/ehz727. Eur Heart J. 2020. PMID: 31630160
Taking One Step Back in Familial Hypercholesterolemia: STAP1 Does Not Alter Plasma LDL (Low-Density Lipoprotein) Cholesterol in Mice and Humans.
Loaiza N, Hartgers ML, Reeskamp LF, Balder JW, Rimbert A, Bazioti V, Wolters JC, Winkelmeijer M, Jansen HPG, Dallinga-Thie GM, Volta A, Huijkman N, Smit M, Kloosterhuis N, Koster M, Svendsen AF, van de Sluis B, Hovingh GK, Grefhorst A, Kuivenhoven JA. Loaiza N, et al. Arterioscler Thromb Vasc Biol. 2020 Apr;40(4):973-985. doi: 10.1161/ATVBAHA.119.313470. Epub 2020 Jan 30. Arterioscler Thromb Vasc Biol. 2020. PMID: 31996024 Free PMC article.
Cholangiopathy and Biliary Fibrosis in Cyp2c70-Deficient Mice Are Fully Reversed by Ursodeoxycholic Acid.
de Boer JF, de Vries HD, Palmiotti A, Li R, Doestzada M, Hoogerland JA, Fu J, La Rose AM, Westerterp M, Mulder NL, Hovingh MV, Koehorst M, Kloosterhuis NJ, Wolters JC, Bloks VW, Haas JT, Dombrowicz D, Staels B, van de Sluis B, Kuipers F. de Boer JF, et al. Among authors: kloosterhuis nj. Cell Mol Gastroenterol Hepatol. 2021;11(4):1045-1069. doi: 10.1016/j.jcmgh.2020.12.004. Epub 2020 Dec 10. Cell Mol Gastroenterol Hepatol. 2021. PMID: 33309945 Free PMC article.
42 results