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Discovery of Targets for Immune-Metabolic Antitumor Drugs Identifies Estrogen-Related Receptor Alpha.
Cancer Discov. 2023 Mar 1;13(3):672-701. doi: 10.1158/2159-8290.CD-22-0244.
Cancer Discov. 2023.
PMID: 36745048
Free PMC article.
Estrogen-related receptor alpha drives mitochondrial biogenesis and resistance to neoadjuvant chemoradiation in esophageal cancer.
Dings MPG, van der Zalm AP, Bootsma S, van Maanen TFJ, Waasdorp C, van den Ende T, Liu D, Bailey P, Koster J, Zwijnenburg DA, Spek CA, Klomp JPG, Oubrie A, Hooijer GKJ, Meijer SL, van Berge Henegouwen MI, Hulshof MC, Bergman J, Oyarce C, Medema JP, van Laarhoven HWM, Bijlsma MF.
Dings MPG, et al. Among authors: klomp jpg.
Cell Rep Med. 2022 Nov 15;3(11):100802. doi: 10.1016/j.xcrm.2022.100802. Epub 2022 Nov 4.
Cell Rep Med. 2022.
PMID: 36334593
Free PMC article.
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Exploiting a subtype-specific mitochondrial vulnerability for successful treatment of colorectal peritoneal metastases.
Bootsma S, Dings MPG, Kesselaar J, Helderman RFCPA, van Megesen K, Constantinides A, Moreno LF, Stelloo E, Scutigliani EM, Bokan B, Torang A, van Hooff SR, Zwijnenburg DA, Wouters VM, van de Vlasakker VCJ, Galanos LJK, Nijman LE, Logiantara A, Veenstra VL, Schlingemann S, van Piggelen S, van der Wel N, Krawczyk PM, Platteeuw JJ, Tuynman JB, de Hingh IH, Klomp JPG, Oubrie A, Snaebjornsson P, Medema JP, Oei AL, Kranenburg O, Elbers CC, Lenos KJ, Vermeulen L, Bijlsma MF.
Bootsma S, et al. Among authors: klomp jpg.
Cell Rep Med. 2024 Apr 22:101523. doi: 10.1016/j.xcrm.2024.101523. Online ahead of print.
Cell Rep Med. 2024.
PMID: 38670098
Free article.
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Comparative analysis of pharmacophore screening tools.
Sanders MP, Barbosa AJ, Zarzycka B, Nicolaes GA, Klomp JP, de Vlieg J, Del Rio A.
Sanders MP, et al.
J Chem Inf Model. 2012 Jun 25;52(6):1607-20. doi: 10.1021/ci2005274. Epub 2012 Jun 13.
J Chem Inf Model. 2012.
PMID: 22646988
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A prospective cross-screening study on G-protein-coupled receptors: lessons learned in virtual compound library design.
Sanders MP, Roumen L, van der Horst E, Lane JR, Vischer HF, van Offenbeek J, de Vries H, Verhoeven S, Chow KY, Verkaar F, Beukers MW, McGuire R, Leurs R, Ijzerman AP, de Vlieg J, de Esch IJ, Zaman GJ, Klomp JP, Bender A, de Graaf C.
Sanders MP, et al.
J Med Chem. 2012 Jun 14;55(11):5311-25. doi: 10.1021/jm300280e. Epub 2012 May 23.
J Med Chem. 2012.
PMID: 22563707
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Snooker: a structure-based pharmacophore generation tool applied to class A GPCRs.
Sanders MP, Verhoeven S, de Graaf C, Roumen L, Vroling B, Nabuurs SB, de Vlieg J, Klomp JP.
Sanders MP, et al.
J Chem Inf Model. 2011 Sep 26;51(9):2277-92. doi: 10.1021/ci200088d. Epub 2011 Sep 6.
J Chem Inf Model. 2011.
PMID: 21866955
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ss-TEA: Entropy based identification of receptor specific ligand binding residues from a multiple sequence alignment of class A GPCRs.
Sanders MP, Fleuren WW, Verhoeven S, van den Beld S, Alkema W, de Vlieg J, Klomp JP.
Sanders MP, et al.
BMC Bioinformatics. 2011 Aug 10;12:332. doi: 10.1186/1471-2105-12-332.
BMC Bioinformatics. 2011.
PMID: 21831265
Free PMC article.
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