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Targeting an RNA-Binding Protein Network in Acute Myeloid Leukemia.
Wang E, Lu SX, Pastore A, Chen X, Imig J, Chun-Wei Lee S, Hockemeyer K, Ghebrechristos YE, Yoshimi A, Inoue D, Ki M, Cho H, Bitner L, Kloetgen A, Lin KT, Uehara T, Owa T, Tibes R, Krainer AR, Abdel-Wahab O, Aifantis I. Wang E, et al. Among authors: kloetgen a. Cancer Cell. 2019 Mar 18;35(3):369-384.e7. doi: 10.1016/j.ccell.2019.01.010. Epub 2019 Feb 21. Cancer Cell. 2019. PMID: 30799057 Free PMC article.
Targeting Mitochondrial Structure Sensitizes Acute Myeloid Leukemia to Venetoclax Treatment.
Chen X, Glytsou C, Zhou H, Narang S, Reyna DE, Lopez A, Sakellaropoulos T, Gong Y, Kloetgen A, Yap YS, Wang E, Gavathiotis E, Tsirigos A, Tibes R, Aifantis I. Chen X, et al. Among authors: kloetgen a. Cancer Discov. 2019 Jul;9(7):890-909. doi: 10.1158/2159-8290.CD-19-0117. Epub 2019 May 2. Cancer Discov. 2019. PMID: 31048321 Free PMC article.
3D Chromosomal Landscapes in Hematopoiesis and Immunity.
Kloetgen A, Thandapani P, Tsirigos A, Aifantis I. Kloetgen A, et al. Trends Immunol. 2019 Sep;40(9):809-824. doi: 10.1016/j.it.2019.07.003. Epub 2019 Aug 15. Trends Immunol. 2019. PMID: 31422902 Free PMC article. Review.
Therapeutic targeting of the E3 ubiquitin ligase SKP2 in T-ALL.
Rodriguez S, Abundis C, Boccalatte F, Mehrotra P, Chiang MY, Yui MA, Wang L, Zhang H, Zollman A, Bonfim-Silva R, Kloetgen A, Palmer J, Sandusky G, Wunderlich M, Kaplan MH, Mulloy JC, Marcucci G, Aifantis I, Cardoso AA, Carlesso N. Rodriguez S, et al. Among authors: kloetgen a. Leukemia. 2020 May;34(5):1241-1252. doi: 10.1038/s41375-019-0653-z. Epub 2019 Nov 26. Leukemia. 2020. PMID: 31772299 Free PMC article.
Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis.
Hanniford D, Ulloa-Morales A, Karz A, Berzoti-Coelho MG, Moubarak RS, Sánchez-Sendra B, Kloetgen A, Davalos V, Imig J, Wu P, Vasudevaraja V, Argibay D, Lilja K, Tabaglio T, Monteagudo C, Guccione E, Tsirigos A, Osman I, Aifantis I, Hernando E. Hanniford D, et al. Among authors: kloetgen a. Cancer Cell. 2020 Jan 13;37(1):55-70.e15. doi: 10.1016/j.ccell.2019.12.007. Cancer Cell. 2020. PMID: 31935372 Free PMC article.
Three-dimensional chromatin landscapes in T cell acute lymphoblastic leukemia.
Kloetgen A, Thandapani P, Ntziachristos P, Ghebrechristos Y, Nomikou S, Lazaris C, Chen X, Hu H, Bakogianni S, Wang J, Fu Y, Boccalatte F, Zhong H, Paietta E, Trimarchi T, Zhu Y, Van Vlierberghe P, Inghirami GG, Lionnet T, Aifantis I, Tsirigos A. Kloetgen A, et al. Nat Genet. 2020 Apr;52(4):388-400. doi: 10.1038/s41588-020-0602-9. Epub 2020 Mar 23. Nat Genet. 2020. PMID: 32203470 Free PMC article.
Surface antigen-guided CRISPR screens identify regulators of myeloid leukemia differentiation.
Wang E, Zhou H, Nadorp B, Cayanan G, Chen X, Yeaton AH, Nomikou S, Witkowski MT, Narang S, Kloetgen A, Thandapani P, Ravn-Boess N, Tsirigos A, Aifantis I. Wang E, et al. Among authors: kloetgen a. Cell Stem Cell. 2021 Apr 1;28(4):718-731.e6. doi: 10.1016/j.stem.2020.12.005. Epub 2021 Jan 14. Cell Stem Cell. 2021. PMID: 33450187 Free PMC article.
Valine tRNA levels and availability regulate complex I assembly in leukaemia.
Thandapani P, Kloetgen A, Witkowski MT, Glytsou C, Lee AK, Wang E, Wang J, LeBoeuf SE, Avrampou K, Papagiannakopoulos T, Tsirigos A, Aifantis I. Thandapani P, et al. Among authors: kloetgen a. Nature. 2022 Jan;601(7893):428-433. doi: 10.1038/s41586-021-04244-1. Epub 2021 Dec 22. Nature. 2022. PMID: 34937946 Free PMC article.
44 results