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Single-cell transcriptomics reveals common epithelial response patterns in human acute kidney injury.
Hinze C, Kocks C, Leiz J, Karaiskos N, Boltengagen A, Cao S, Skopnik CM, Klocke J, Hardenberg JH, Stockmann H, Gotthardt I, Obermayer B, Haghverdi L, Wyler E, Landthaler M, Bachmann S, Hocke AC, Corman V, Busch J, Schneider W, Himmerkus N, Bleich M, Eckardt KU, Enghard P, Rajewsky N, Schmidt-Ott KM. Hinze C, et al. Among authors: klocke j. Genome Med. 2022 Sep 9;14(1):103. doi: 10.1186/s13073-022-01108-9. Genome Med. 2022. PMID: 36085050 Free PMC article.
Urinary CD4 T cells identify SLE patients with proliferative lupus nephritis and can be used to monitor treatment response.
Enghard P, Rieder C, Kopetschke K, Klocke JR, Undeutsch R, Biesen R, Dragun D, Gollasch M, Schneider U, Aupperle K, Humrich JY, Hiepe F, Backhaus M, Radbruch AH, Burmester GR, Riemekasten G. Enghard P, et al. Among authors: klocke jr. Ann Rheum Dis. 2014 Jan;73(1):277-83. doi: 10.1136/annrheumdis-2012-202784. Epub 2013 Mar 8. Ann Rheum Dis. 2014. PMID: 23475982 Clinical Trial.
Urinary CD8+HLA-DR+ T Cell Abundance Non-invasively Predicts Kidney Transplant Rejection.
Grothgar E, Goerlich N, Samans B, Skopnik CM, Metzke D, Klocke J, Prskalo L, Freund P, Wagner L, Duerr M, Matz M, Olek S, Budde K, Paliege A, Enghard P. Grothgar E, et al. Among authors: klocke j. Front Med (Lausanne). 2022 Jul 15;9:928516. doi: 10.3389/fmed.2022.928516. eCollection 2022. Front Med (Lausanne). 2022. PMID: 35911418 Free PMC article.
Urinary single-cell sequencing captures kidney injury and repair processes in human acute kidney injury.
Klocke J, Kim SJ, Skopnik CM, Hinze C, Boltengagen A, Metzke D, Grothgar E, Prskalo L, Wagner L, Freund P, Görlich N, Muench F, Schmidt-Ott KM, Mashreghi MF, Kocks C, Eckardt KU, Rajewsky N, Enghard P. Klocke J, et al. Kidney Int. 2022 Dec;102(6):1359-1370. doi: 10.1016/j.kint.2022.07.032. Epub 2022 Aug 29. Kidney Int. 2022. PMID: 36049643 Free article.
Tubular Epithelial Cell HMGB1 Promotes AKI-CKD Transition by Sensitizing Cycling Tubular Cells to Oxidative Stress: A Rationale for Targeting HMGB1 during AKI Recovery.
Zhao ZB, Marschner JA, Iwakura T, Li C, Motrapu M, Kuang M, Popper B, Linkermann A, Klocke J, Enghard P, Muto Y, Humphreys BD, Harris HE, Romagnani P, Anders HJ. Zhao ZB, et al. Among authors: klocke j. J Am Soc Nephrol. 2023 Mar 1;34(3):394-411. doi: 10.1681/ASN.0000000000000024. Epub 2023 Jan 17. J Am Soc Nephrol. 2023. PMID: 36857499 Free PMC article.
Addition of formaldehyde releaser imidazolidinyl urea and MOPS buffer to urine samples enables delayed processing for flow cytometric analysis of urinary cells: A simple, two step conservation method of urinary cells for flow cytometry.
Freund P, Skopnik CM, Metzke D, Goerlich N, Klocke J, Grothgar E, Prskalo L, Hiepe F, Enghard P. Freund P, et al. Among authors: klocke j. Cytometry B Clin Cytom. 2023 Nov;104(6):417-425. doi: 10.1002/cyto.b.22117. Epub 2023 Mar 7. Cytometry B Clin Cytom. 2023. PMID: 36880455
Urinary T Cells Identify Renal Antineutrophil Cytoplasmic Antibody-Associated Vasculitis and Predict Prognosis: A Proof of Concept Study.
Sonnemann J, Klocke J, Bieringer M, Rousselle A, Eckardt KU, Elitok S, Popovic S, Bachmann S, Kettritz R, Salama AD, Enghard P, Schreiber A. Sonnemann J, et al. Among authors: klocke j. Kidney Int Rep. 2023 Jan 18;8(4):871-883. doi: 10.1016/j.ekir.2023.01.013. eCollection 2023 Apr. Kidney Int Rep. 2023. PMID: 37069968 Free PMC article.
38 results