Klitgaard JK - Search Results

1

Insight Into the Anti-staphylococcal Activity of JBC 1847 at Sub-Inhibitory Concentration.

Ronco T, Kappel LH, Aragao MF, Biagi N, Svenningsen S, Christensen JB, Permin A, Saaby L, Holmstrøm K, Klitgaard JK, Sabat AJ, Akkerboom V, Monaco M, Tinelli M, Friedrich AW, Jana B, Olsen RH. Ronco T, et al. Among authors: klitgaard jk. Front Microbiol. 2022 Jan 5;12:786173. doi: 10.3389/fmicb.2021.786173. eCollection 2021. Front Microbiol. 2022. PMID: 35069485 Free PMC article.

2

Thioridazine affects transcription of genes involved in cell wall biosynthesis in methicillin-resistant Staphylococcus aureus.

Bonde M, Højland DH, Kolmos HJ, Kallipolitis BH, Klitgaard JK. Bonde M, et al. Among authors: klitgaard jk. FEMS Microbiol Lett. 2011 May;318(2):168-76. doi: 10.1111/j.1574-6968.2011.02255.x. Epub 2011 Mar 25. FEMS Microbiol Lett. 2011. PMID: 21375577

3

Combination therapy with thioridazine and dicloxacillin combats meticillin-resistant Staphylococcus aureus infection in Caenorhabditis elegans.

Poulsen MØ, Schøler L, Nielsen A, Skov MN, Kolmos HJ, Kallipolitis BH, Olsen A, Klitgaard JK. Poulsen MØ, et al. Among authors: klitgaard jk. J Med Microbiol. 2014 Sep;63(Pt 9):1174-1180. doi: 10.1099/jmm.0.071837-0. Epub 2014 Jun 9. J Med Microbiol. 2014. PMID: 24913562

4

Thioridazine potentiates the effect of a beta-lactam antibiotic against Staphylococcus aureus independently of mecA expression.

Poulsen MØ, Jacobsen K, Thorsing M, Kristensen NR, Clasen J, Lillebæk EM, Skov MN, Kallipolitis BH, Kolmos HJ, Klitgaard JK. Poulsen MØ, et al. Among authors: klitgaard jk. Res Microbiol. 2013 Feb-Mar;164(2):181-8. doi: 10.1016/j.resmic.2012.10.007. Epub 2012 Oct 23. Res Microbiol. 2013. PMID: 23089256 Free article.

5

Thioridazine induces major changes in global gene expression and cell wall composition in methicillin-resistant Staphylococcus aureus USA300.

Thorsing M, Klitgaard JK, Atilano ML, Skov MN, Kolmos HJ, Filipe SR, Kallipolitis BH. Thorsing M, et al. Among authors: klitgaard jk. PLoS One. 2013 May 17;8(5):e64518. doi: 10.1371/journal.pone.0064518. Print 2013. PLoS One. 2013. PMID: 23691239 Free PMC article.

6

Combination of thioridazine and dicloxacillin as a possible treatment strategy of staphylococci.

Rasmussen KS, Poulsen MØ, Jacobsen K, Skov MN, Kolmos HJ, Kallipolitis BH, Klitgaard JK. Rasmussen KS, et al. Among authors: klitgaard jk. New Microbiol. 2017 Apr;40(2):146-147. Epub 2017 Mar 1. New Microbiol. 2017. PMID: 28255602 Free article.

7

Molecular mechanisms of thioridazine resistance in Staphylococcus aureus.

Wassmann CS, Lund LC, Thorsing M, Lauritzen SP, Kolmos HJ, Kallipolitis BH, Klitgaard JK. Wassmann CS, et al. Among authors: klitgaard jk. PLoS One. 2018 Aug 8;13(8):e0201767. doi: 10.1371/journal.pone.0201767. eCollection 2018. PLoS One. 2018. PMID: 30089175 Free PMC article.

8

Cannabidiol is an effective helper compound in combination with bacitracin to kill Gram-positive bacteria.

Wassmann CS, Højrup P, Klitgaard JK. Wassmann CS, et al. Among authors: klitgaard jk. Sci Rep. 2020 Mar 5;10(1):4112. doi: 10.1038/s41598-020-60952-0. Sci Rep. 2020. PMID: 32139776 Free PMC article.

9

Discovery of a Potent Adenine-Benzyltriazolo-Pleuromutilin Conjugate with Pronounced Antibacterial Activity against MRSA.

Heidtmann CV, Voukia F, Hansen LN, Sørensen SH, Urlund B, Nielsen S, Pedersen M, Kelawi N, Andersen BN, Pedersen M, Reinholdt P, Kongsted J, Nielsen CU, Klitgaard JK, Nielsen P. Heidtmann CV, et al. Among authors: klitgaard jk. J Med Chem. 2020 Dec 24;63(24):15693-15708. doi: 10.1021/acs.jmedchem.0c01328. Epub 2020 Dec 16. J Med Chem. 2020. PMID: 33325700

10

The menaquinone pathway is important for susceptibility of Staphylococcus aureus to the antibiotic adjuvant, cannabidiol.

Wassmann CS, Rolsted AP, Lyngsie MC, Torres-Puig S, Kronborg T, Vestergaard M, Ingmer H, Pontoppidan SP, Klitgaard JK. Wassmann CS, et al. Among authors: klitgaard jk. Microbiol Res. 2022 Apr;257:126974. doi: 10.1016/j.micres.2022.126974. Epub 2022 Jan 19. Microbiol Res. 2022. PMID: 35091344 Free article.

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