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Page 1
Reduced mitochondrial resilience enables non-canonical induction of apoptosis after TNF receptor signaling in virus-infected hepatocytes.
Lampl S, Janas MK, Donakonda S, Brugger M, Lohr K, Schneider A, Manske K, Sperl LE, Kläger S, Küster B, Wettmarshausen J, Müller C, Laschinger M, Hartmann D, Hüser N, Perocchi F, Schmitt-Kopplin P, Hagn F, Zender L, Hornung V, Borner C, Pichlmair A, Kashkar H, Klingenspor M, Prinz M, Schreiner S, Conrad M, Jost PJ, Zischka H, Steiger K, Krönke M, Zehn D, Protzer U, Heikenwälder M, Knolle PA, Wohlleber D. Lampl S, et al. Among authors: klingenspor m. J Hepatol. 2020 Dec;73(6):1347-1359. doi: 10.1016/j.jhep.2020.06.026. Epub 2020 Jun 26. J Hepatol. 2020. PMID: 32598967
Mitochondrial function controls intestinal epithelial stemness and proliferation.
Berger E, Rath E, Yuan D, Waldschmitt N, Khaloian S, Allgäuer M, Staszewski O, Lobner EM, Schöttl T, Giesbertz P, Coleman OI, Prinz M, Weber A, Gerhard M, Klingenspor M, Janssen KP, Heikenwalder M, Haller D. Berger E, et al. Among authors: klingenspor m. Nat Commun. 2016 Oct 27;7:13171. doi: 10.1038/ncomms13171. Nat Commun. 2016. PMID: 27786175 Free PMC article.
The exceptional sensitivity of brain mitochondria to copper.
Borchard S, Bork F, Rieder T, Eberhagen C, Popper B, Lichtmannegger J, Schmitt S, Adamski J, Klingenspor M, Weiss KH, Zischka H. Borchard S, et al. Among authors: klingenspor m. Toxicol In Vitro. 2018 Sep;51:11-22. doi: 10.1016/j.tiv.2018.04.012. Epub 2018 Apr 30. Toxicol In Vitro. 2018. PMID: 29715505 Free article.
Loss of UCP1 function augments recruitment of futile lipid cycling for thermogenesis in murine brown fat.
Oeckl J, Janovska P, Adamcova K, Bardova K, Brunner S, Dieckmann S, Ecker J, Fromme T, Funda J, Gantert T, Giansanti P, Hidrobo MS, Kuda O, Kuster B, Li Y, Pohl R, Schmitt S, Schweizer S, Zischka H, Zouhar P, Kopecky J, Klingenspor M. Oeckl J, et al. Among authors: klingenspor m. Mol Metab. 2022 Jul;61:101499. doi: 10.1016/j.molmet.2022.101499. Epub 2022 Apr 22. Mol Metab. 2022. PMID: 35470094 Free PMC article.
Distinct signatures of host-microbial meta-metabolome and gut microbiome in two C57BL/6 strains under high-fat diet.
Walker A, Pfitzner B, Neschen S, Kahle M, Harir M, Lucio M, Moritz F, Tziotis D, Witting M, Rothballer M, Engel M, Schmid M, Endesfelder D, Klingenspor M, Rattei T, Castell WZ, de Angelis MH, Hartmann A, Schmitt-Kopplin P. Walker A, et al. Among authors: klingenspor m. ISME J. 2014 Dec;8(12):2380-96. doi: 10.1038/ismej.2014.79. Epub 2014 Jun 6. ISME J. 2014. PMID: 24906017 Free PMC article.
Treatment of diet-induced lipodystrophic C57BL/6J mice with long-acting PASylated leptin normalises insulin sensitivity and hepatic steatosis by promoting lipid utilisation.
Bolze F, Bast A, Mocek S, Morath V, Yuan D, Rink N, Schlapschy M, Zimmermann A, Heikenwalder M, Skerra A, Klingenspor M. Bolze F, et al. Among authors: klingenspor m. Diabetologia. 2016 Sep;59(9):2005-12. doi: 10.1007/s00125-016-4004-6. Epub 2016 Jun 7. Diabetologia. 2016. PMID: 27272237
Dietary fat and gut microbiota interactions determine diet-induced obesity in mice.
Kübeck R, Bonet-Ripoll C, Hoffmann C, Walker A, Müller VM, Schüppel VL, Lagkouvardos I, Scholz B, Engel KH, Daniel H, Schmitt-Kopplin P, Haller D, Clavel T, Klingenspor M. Kübeck R, et al. Among authors: klingenspor m. Mol Metab. 2016 Oct 13;5(12):1162-1174. doi: 10.1016/j.molmet.2016.10.001. eCollection 2016 Dec. Mol Metab. 2016. PMID: 27900259 Free PMC article.
Disturbed gut microbiota and bile homeostasis in Giardia-infected mice contributes to metabolic dysregulation and growth impairment.
Riba A, Hassani K, Walker A, van Best N, von Zezschwitz D, Anslinger T, Sillner N, Rosenhain S, Eibach D, Maiga-Ascofaré O, Rolle-Kampczyk U, Basic M, Binz A, Mocek S, Sodeik B, Bauerfeind R, Mohs A, Trautwein C, Kiessling F, May J, Klingenspor M, Gremse F, Schmitt-Kopplin P, Bleich A, Torow N, von Bergen M, Hornef MW. Riba A, et al. Among authors: klingenspor m. Sci Transl Med. 2020 Oct 14;12(565):eaay7019. doi: 10.1126/scitranslmed.aay7019. Sci Transl Med. 2020. PMID: 33055245
238 results