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Page 1
Loss of Kmt2c in vivo leads to EMT, mitochondrial dysfunction and improved response to lapatinib in breast cancer.
Simigdala N, Chalari A, Sklirou AD, Chavdoula E, Papafotiou G, Melissa P, Kafalidou A, Paschalidis N, Pateras IS, Athanasiadis E, Konstantopoulos D, Trougakos IP, Klinakis A. Simigdala N, et al. Among authors: klinakis a. Cell Mol Life Sci. 2023 Mar 18;80(4):100. doi: 10.1007/s00018-023-04734-7. Cell Mol Life Sci. 2023. PMID: 36933062 Free PMC article.
Functional interplay between the DNA-damage-response kinase ATM and ARF tumour suppressor protein in human cancer.
Velimezi G, Liontos M, Vougas K, Roumeliotis T, Bartkova J, Sideridou M, Dereli-Oz A, Kocylowski M, Pateras IS, Evangelou K, Kotsinas A, Orsolic I, Bursac S, Cokaric-Brdovcak M, Zoumpourlis V, Kletsas D, Papafotiou G, Klinakis A, Volarevic S, Gu W, Bartek J, Halazonetis TD, Gorgoulis VG. Velimezi G, et al. Among authors: klinakis a. Nat Cell Biol. 2013 Aug;15(8):967-77. doi: 10.1038/ncb2795. Epub 2013 Jul 14. Nat Cell Biol. 2013. PMID: 23851489
The DNA damage checkpoint precedes activation of ARF in response to escalating oncogenic stress during tumorigenesis.
Evangelou K, Bartkova J, Kotsinas A, Pateras IS, Liontos M, Velimezi G, Kosar M, Liloglou T, Trougakos IP, Dyrskjot L, Andersen CL, Papaioannou M, Drosos Y, Papafotiou G, Hodny Z, Sosa-Pineda B, Wu XR, Klinakis A, Ørntoft T, Lukas J, Bartek J, Gorgoulis VG. Evangelou K, et al. Among authors: klinakis a. Cell Death Differ. 2013 Nov;20(11):1485-97. doi: 10.1038/cdd.2013.76. Epub 2013 Jul 12. Cell Death Differ. 2013. PMID: 23852374 Free PMC article.
KRT14 marks bladder progenitors.
Paraskevopoulou V, Papafotiou G, Klinakis A. Paraskevopoulou V, et al. Among authors: klinakis a. Cell Cycle. 2016 Dec;15(23):3161-3162. doi: 10.1080/15384101.2016.1220722. Epub 2016 Aug 22. Cell Cycle. 2016. PMID: 27548378 Free PMC article. No abstract available.
Molecular mechanisms of carfilzomib-induced cardiotoxicity in mice and the emerging cardioprotective role of metformin.
Efentakis P, Kremastiotis G, Varela A, Nikolaou PE, Papanagnou ED, Davos CH, Tsoumani M, Agrogiannis G, Konstantinidou A, Kastritis E, Kanaki Z, Iliodromitis EK, Klinakis A, Dimopoulos MA, Trougakos IP, Andreadou I, Terpos E. Efentakis P, et al. Among authors: klinakis a. Blood. 2019 Feb 14;133(7):710-723. doi: 10.1182/blood-2018-06-858415. Epub 2018 Nov 27. Blood. 2019. PMID: 30482794 Free article.
The lysine-specific methyltransferase KMT2C/MLL3 regulates DNA repair components in cancer.
Rampias T, Karagiannis D, Avgeris M, Polyzos A, Kokkalis A, Kanaki Z, Kousidou E, Tzetis M, Kanavakis E, Stravodimos K, Manola KN, Pantelias GE, Scorilas A, Klinakis A. Rampias T, et al. Among authors: klinakis a. EMBO Rep. 2019 Mar;20(3):e46821. doi: 10.15252/embr.201846821. Epub 2019 Jan 21. EMBO Rep. 2019. PMID: 30665945 Free PMC article.
Levosimendan prevents doxorubicin-induced cardiotoxicity in time- and dose-dependent manner: implications for inotropy.
Efentakis P, Varela A, Chavdoula E, Sigala F, Sanoudou D, Tenta R, Gioti K, Kostomitsopoulos N, Papapetropoulos A, Tasouli A, Farmakis D, Davos CH, Klinakis A, Suter T, Cokkinos DV, Iliodromitis EK, Wenzel P, Andreadou I. Efentakis P, et al. Among authors: klinakis a. Cardiovasc Res. 2020 Mar 1;116(3):576-591. doi: 10.1093/cvr/cvz163. Cardiovasc Res. 2020. PMID: 31228183
61 results