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A new tumor suppressor role for the Notch pathway in bladder cancer.
Rampias T, Vgenopoulou P, Avgeris M, Polyzos A, Stravodimos K, Valavanis C, Scorilas A, Klinakis A. Rampias T, et al. Among authors: klinakis a. Nat Med. 2014 Oct;20(10):1199-205. doi: 10.1038/nm.3678. Epub 2014 Sep 7. Nat Med. 2014. PMID: 25194568
The lysine-specific methyltransferase KMT2C/MLL3 regulates DNA repair components in cancer.
Rampias T, Karagiannis D, Avgeris M, Polyzos A, Kokkalis A, Kanaki Z, Kousidou E, Tzetis M, Kanavakis E, Stravodimos K, Manola KN, Pantelias GE, Scorilas A, Klinakis A. Rampias T, et al. Among authors: klinakis a. EMBO Rep. 2019 Mar;20(3):e46821. doi: 10.15252/embr.201846821. Epub 2019 Jan 21. EMBO Rep. 2019. PMID: 30665945 Free PMC article.
Loss of Kmt2c in vivo leads to EMT, mitochondrial dysfunction and improved response to lapatinib in breast cancer.
Simigdala N, Chalari A, Sklirou AD, Chavdoula E, Papafotiou G, Melissa P, Kafalidou A, Paschalidis N, Pateras IS, Athanasiadis E, Konstantopoulos D, Trougakos IP, Klinakis A. Simigdala N, et al. Among authors: klinakis a. Cell Mol Life Sci. 2023 Mar 18;80(4):100. doi: 10.1007/s00018-023-04734-7. Cell Mol Life Sci. 2023. PMID: 36933062 Free PMC article.
Therapeutic effects of an anti-Myc drug on mouse pancreatic cancer.
Stellas D, Szabolcs M, Koul S, Li Z, Polyzos A, Anagnostopoulos C, Cournia Z, Tamvakopoulos C, Klinakis A, Efstratiadis A. Stellas D, et al. Among authors: klinakis a. J Natl Cancer Inst. 2014 Oct 11;106(12):dju320. doi: 10.1093/jnci/dju320. Print 2014 Dec. J Natl Cancer Inst. 2014. PMID: 25306215
Functional interplay between the DNA-damage-response kinase ATM and ARF tumour suppressor protein in human cancer.
Velimezi G, Liontos M, Vougas K, Roumeliotis T, Bartkova J, Sideridou M, Dereli-Oz A, Kocylowski M, Pateras IS, Evangelou K, Kotsinas A, Orsolic I, Bursac S, Cokaric-Brdovcak M, Zoumpourlis V, Kletsas D, Papafotiou G, Klinakis A, Volarevic S, Gu W, Bartek J, Halazonetis TD, Gorgoulis VG. Velimezi G, et al. Among authors: klinakis a. Nat Cell Biol. 2013 Aug;15(8):967-77. doi: 10.1038/ncb2795. Epub 2013 Jul 14. Nat Cell Biol. 2013. PMID: 23851489
61 results