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Prothymosin α and its C-Terminal Immunoreactive Decapeptide Show No Evidence of Acute Toxicity: A Preliminary In Silico, In Vitro and In Vivo Investigation.
Birmpilis AI, Vitsos P, Kostopoulos IV, Williams L, Ioannou K, Samara P, Karachaliou CE, Voutsas IF, Alyfanti E, Angelis N, Gavalas NG, Gkraikou T, Kappa N, Klagkou E, Klimentzou P, Nikou S, Papaioannou NE, Skopeliti M, Toukli D, Dimopoulos MA, Bamias A, Livaniou E, Kalbacher H, Tsitsilonis OE, Voelter W. Birmpilis AI, et al. Among authors: klimentzou p. Curr Med Chem. 2022;29(42):6463-6478. doi: 10.2174/0929867328666211117093401. Curr Med Chem. 2022. PMID: 34789121
The immunologically active site of prothymosin alpha is located at the carboxy-terminus of the polypeptide. Evaluation of its in vitro effects in cancer patients.
Skopeliti M, Voutsas IF, Klimentzou P, Tsiatas ML, Beck A, Bamias A, Moraki M, Livaniou E, Neagu M, Voelter W, Tsitsilonis OE. Skopeliti M, et al. Among authors: klimentzou p. Cancer Immunol Immunother. 2006 Oct;55(10):1247-57. doi: 10.1007/s00262-005-0108-4. Epub 2006 Feb 2. Cancer Immunol Immunother. 2006. PMID: 16453152 Free PMC article.
Development of a specific IgY-based ELISA for prothymosin alpha, a bioactive polypeptide with diagnostic and therapeutic potential.
Karachaliou CE, Kostopoulos IV, Vassilakopoulou V, Klimentzou P, Paravatou-Petsotas M, Voelter W, Kalbacher H, Zikos C, Tsitsilonis O, Livaniou E. Karachaliou CE, et al. Among authors: klimentzou p. Heliyon. 2019 Nov 1;5(10):e02616. doi: 10.1016/j.heliyon.2019.e02616. eCollection 2019 Oct. Heliyon. 2019. PMID: 31720448 Free PMC article.
Immunological potential of Helix vulgaris and Rapana venosa hemocyanins.
Dolashka-Angelova P, Stefanova T, Livaniou E, Velkova L, Klimentzou P, Stevanovic S, Salvato B, Neychev H, Voelter W. Dolashka-Angelova P, et al. Among authors: klimentzou p. Immunol Invest. 2008;37(8):822-40. doi: 10.1080/08820130802403366. Immunol Invest. 2008. PMID: 18991098
Thermal unfolding of human BRCA1 BRCT-domain variants.
Nikolopoulos G, Pyrpassopoulos S, Thanassoulas A, Klimentzou P, Zikos C, Vlassi M, Vorgias CE, Yannoukakos D, Nounesis G. Nikolopoulos G, et al. Among authors: klimentzou p. Biochim Biophys Acta. 2007 Jun;1774(6):772-80. doi: 10.1016/j.bbapap.2007.03.018. Epub 2007 Apr 6. Biochim Biophys Acta. 2007. PMID: 17493881