Kless A - Search Results

1

Investigating targets for neuropharmacological intervention by molecular dynamics simulations.

Rossetti G, Kless A, Lai L, Outeiro TF, Carloni P. Rossetti G, et al. Among authors: kless a. Biochem Soc Trans. 2019 Jun 28;47(3):909-918. doi: 10.1042/BST20190048. Epub 2019 May 13. Biochem Soc Trans. 2019. PMID: 31085614 Review.

2

Structural Prediction of the Dimeric Form of the Mammalian Translocator Membrane Protein TSPO: A Key Target for Brain Diagnostics.

Zeng J, Guareschi R, Damre M, Cao R, Kless A, Neumaier B, Bauer A, Giorgetti A, Carloni P, Rossetti G. Zeng J, et al. Among authors: kless a. Int J Mol Sci. 2018 Aug 31;19(9):2588. doi: 10.3390/ijms19092588. Int J Mol Sci. 2018. PMID: 30200318 Free PMC article.

3

Structural heterogeneity of the μ-opioid receptor's conformational ensemble in the apo state.

Sena DM Jr, Cong X, Giorgetti A, Kless A, Carloni P. Sena DM Jr, et al. Among authors: kless a. Sci Rep. 2017 Apr 3;8:45761. doi: 10.1038/srep45761. Sci Rep. 2017. PMID: 28368046 Free PMC article.

4

Structural Determinants for the Binding of Morphinan Agonists to the μ-Opioid Receptor.

Cong X, Campomanes P, Kless A, Schapitz I, Wagener M, Koch T, Carloni P. Cong X, et al. Among authors: kless a. PLoS One. 2015 Aug 17;10(8):e0135998. doi: 10.1371/journal.pone.0135998. eCollection 2015. PLoS One. 2015. PMID: 26280453 Free PMC article.

5

Thiol dependent intramolecular locking of Orai1 channels.

Alansary D, Schmidt B, Dörr K, Bogeski I, Rieger H, Kless A, Niemeyer BA. Alansary D, et al. Among authors: kless a. Sci Rep. 2016 Sep 14;6:33347. doi: 10.1038/srep33347. Sci Rep. 2016. PMID: 27624281 Free PMC article.

6

Molecular determinants of potent P2X2 antagonism identified by functional analysis, mutagenesis, and homology docking.

Wolf C, Rosefort C, Fallah G, Kassack MU, Hamacher A, Bodnar M, Wang H, Illes P, Kless A, Bahrenberg G, Schmalzing G, Hausmann R. Wolf C, et al. Among authors: kless a. Mol Pharmacol. 2011 Apr;79(4):649-61. doi: 10.1124/mol.110.068700. Epub 2010 Dec 29. Mol Pharmacol. 2011. PMID: 21191044

7

Discovery of Spiro[cyclohexane-dihydropyrano[3,4-b]indole]-amines as Potent NOP and Opioid Receptor Agonists.

Schunk S, Linz K, Frormann S, Hinze C, Oberbörsch S, Sundermann B, Zemolka S, Englberger W, Germann T, Christoph T, Kögel BY, Schröder W, Harlfinger S, Saunders D, Kless A, Schick H, Sonnenschein H. Schunk S, et al. Among authors: kless a. ACS Med Chem Lett. 2014 Jun 24;5(8):851-6. doi: 10.1021/ml500116x. eCollection 2014 Aug 14. ACS Med Chem Lett. 2014. PMID: 25147602 Free PMC article.

8

Key sites for P2X receptor function and multimerization: overview of mutagenesis studies on a structural basis.

Hausmann R, Kless A, Schmalzing G. Hausmann R, et al. Among authors: kless a. Curr Med Chem. 2015;22(7):799-818. doi: 10.2174/0929867322666141128163215. Curr Med Chem. 2015. PMID: 25439586 Free PMC article. Review.

9

Identification of aurintricarboxylic acid as a potent allosteric antagonist of P2X1 and P2X3 receptors.

Obrecht AS, Urban N, Schaefer M, Röse A, Kless A, Meents JE, Lampert A, Abdelrahman A, Müller CE, Schmalzing G, Hausmann R. Obrecht AS, et al. Among authors: kless a. Neuropharmacology. 2019 Nov 1;158:107749. doi: 10.1016/j.neuropharm.2019.107749. Epub 2019 Aug 25. Neuropharmacology. 2019. PMID: 31461640

10

Heteromeric assembly of P2X subunits.

Saul A, Hausmann R, Kless A, Nicke A. Saul A, et al. Among authors: kless a. Front Cell Neurosci. 2013 Dec 18;7:250. doi: 10.3389/fncel.2013.00250. Front Cell Neurosci. 2013. PMID: 24391538 Free PMC article. Review.

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