Klement JD - Search Results

1

Restoring FAS Expression via Lipid-Encapsulated FAS DNA Nanoparticle Delivery Is Sufficient to Suppress Colon Tumor Growth In Vivo.

Merting AD, Poschel DB, Lu C, Klement JD, Yang D, Li H, Shi H, Chapdelaine E, Montgomery M, Redman MT, Savage NM, Nayak-Kapoor A, Liu K. Merting AD, et al. Among authors: klement jd. Cancers (Basel). 2022 Jan 12;14(2):361. doi: 10.3390/cancers14020361. Cancers (Basel). 2022. PMID: 35053524 Free PMC article.

2

SETD1B Activates iNOS Expression in Myeloid-Derived Suppressor Cells.

Redd PS, Ibrahim ML, Klement JD, Sharman SK, Paschall AV, Yang D, Nayak-Kapoor A, Liu K. Redd PS, et al. Among authors: klement jd. Cancer Res. 2017 Jun 1;77(11):2834-2843. doi: 10.1158/0008-5472.CAN-16-2238. Epub 2017 Apr 5. Cancer Res. 2017. PMID: 28381543 Free PMC article.

3

IFNAR1 Controls Autocrine Type I IFN Regulation of PD-L1 Expression in Myeloid-Derived Suppressor Cells.

Xiao W, Klement JD, Lu C, Ibrahim ML, Liu K. Xiao W, et al. Among authors: klement jd. J Immunol. 2018 Jul 1;201(1):264-277. doi: 10.4049/jimmunol.1800129. Epub 2018 May 11. J Immunol. 2018. PMID: 29752314 Free PMC article.

4

H3K4me3 mediates the NF-κB p50 homodimer binding to the pdcd1 promoter to activate PD-1 transcription in T cells.

Redd PS, Lu C, Klement JD, Ibrahim ML, Zhou G, Kumai T, Celis E, Liu K. Redd PS, et al. Among authors: klement jd. Oncoimmunology. 2018 Jul 23;7(9):e1483302. doi: 10.1080/2162402X.2018.1483302. eCollection 2018. Oncoimmunology. 2018. PMID: 30228953 Free PMC article.

5

An osteopontin/CD44 immune checkpoint controls CD8+ T cell activation and tumor immune evasion.

Klement JD, Paschall AV, Redd PS, Ibrahim ML, Lu C, Yang D, Celis E, Abrams SI, Ozato K, Liu K. Klement JD, et al. J Clin Invest. 2018 Dec 3;128(12):5549-5560. doi: 10.1172/JCI123360. Epub 2018 Nov 5. J Clin Invest. 2018. PMID: 30395540 Free PMC article.

6

Loss of Fas Expression and Function Is Coupled with Colon Cancer Resistance to Immune Checkpoint Inhibitor Immunotherapy.

Xiao W, Ibrahim ML, Redd PS, Klement JD, Lu C, Yang D, Savage NM, Liu K. Xiao W, et al. Among authors: klement jd. Mol Cancer Res. 2019 Feb;17(2):420-430. doi: 10.1158/1541-7786.MCR-18-0455. Epub 2018 Nov 14. Mol Cancer Res. 2019. PMID: 30429213 Free PMC article.

7

Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon Tumorigenesis.

Ibrahim ML, Klement JD, Lu C, Redd PS, Xiao W, Yang D, Browning DD, Savage NM, Buckhaults PJ, Morse HC 3rd, Liu K. Ibrahim ML, et al. Among authors: klement jd. Cell Rep. 2018 Dec 11;25(11):3036-3046.e6. doi: 10.1016/j.celrep.2018.11.050. Cell Rep. 2018. PMID: 30540937 Free PMC article.

8

SUV39H1 Represses the Expression of Cytotoxic T-Lymphocyte Effector Genes to Promote Colon Tumor Immune Evasion.

Lu C, Yang D, Klement JD, Oh IK, Savage NM, Waller JL, Colby AH, Grinstaff MW, Oberlies NH, Pearce CJ, Xie Z, Kulp SK, Coss CC, Phelps MA, Albers T, Lebedyeva IO, Liu K. Lu C, et al. Among authors: klement jd. Cancer Immunol Res. 2019 Mar;7(3):414-427. doi: 10.1158/2326-6066.CIR-18-0126. Epub 2019 Jan 4. Cancer Immunol Res. 2019. PMID: 30610059 Free PMC article.

9

Type I interferon suppresses tumor growth through activating the STAT3-granzyme B pathway in tumor-infiltrating cytotoxic T lymphocytes.

Lu C, Klement JD, Ibrahim ML, Xiao W, Redd PS, Nayak-Kapoor A, Zhou G, Liu K. Lu C, et al. Among authors: klement jd. J Immunother Cancer. 2019 Jun 22;7(1):157. doi: 10.1186/s40425-019-0635-8. J Immunother Cancer. 2019. PMID: 31228946 Free PMC article.

10

SUV39H1 regulates human colon carcinoma apoptosis and cell cycle to promote tumor growth.

Lu C, Klement JD, Yang D, Albers T, Lebedyeva IO, Waller JL, Liu K. Lu C, et al. Among authors: klement jd. Cancer Lett. 2020 Apr 28;476:87-96. doi: 10.1016/j.canlet.2020.02.004. Epub 2020 Feb 12. Cancer Lett. 2020. PMID: 32061753 Free PMC article.

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