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Report of the Assay Guidance Workshop on 3-Dimensional Tissue Models for Antiviral Drug Development.
Jordan R, Ford-Scheimer SL, Alarcon RM, Atala A, Borenstein JT, Brimacombe KR, Cherry S, Clevers H, Davis MI, Funnell SGP, Gehrke L, Griffith LG, Grossman AC, Hartung T, Ingber DE, Kleinstreuer NC, Kuo CJ, Lee EM, Mummery CL, Pickett TE, Ramani S, Rosado-Olivieri EA, Struble EB, Wan Z, Williams MS, Hall MD, Ferrer M, Markossian S. Jordan R, et al. Among authors: kleinstreuer nc. J Infect Dis. 2023 Oct 3;228(Suppl 5):S337-S354. doi: 10.1093/infdis/jiad334. J Infect Dis. 2023. PMID: 37669225 Free PMC article.
Examining animal testing for risk assessment: A WC-12 workshop report.
Bhuller Y, Karmaus A, Kleinstreuer N, Seidle T, Schlatter H, Wade M, Chandrasekera PC. Bhuller Y, et al. Regul Toxicol Pharmacol. 2024 Feb;147:105564. doi: 10.1016/j.yrtph.2024.105564. Epub 2024 Jan 4. Regul Toxicol Pharmacol. 2024. PMID: 38182013 Free article.
60 Years of the 3Rs symposium: Lessons learned and the road ahead.
Balls M, Bass R, Curren R, Fentem J, Goldberg A, Hartung T, Herrmann K, Kleinstreuer NC, Libowitz L, Parascandola J, Rowan A, Spielmann H, Stephens ML, Thomas RS, Tsaioun K. Balls M, et al. Among authors: kleinstreuer nc. ALTEX. 2024;41(2):179-201. doi: 10.14573/altex.2403061. ALTEX. 2024. PMID: 38629803 Free article.
Evaluation of in silico model predictions for mammalian acute oral toxicity and regulatory application in pesticide hazard and risk assessment.
Bishop PL, Mansouri K, Eckel WP, Lowit MB, Allen D, Blankinship A, Lowit AB, Harwood DE, Johnson T, Kleinstreuer NC. Bishop PL, et al. Among authors: kleinstreuer nc. Regul Toxicol Pharmacol. 2024 May;149:105614. doi: 10.1016/j.yrtph.2024.105614. Epub 2024 Apr 2. Regul Toxicol Pharmacol. 2024. PMID: 38574841 Free article.
Defined approaches to classify agrochemical formulations into EPA hazard categories developed using EpiOcularTM reconstructed human corneal epithelium and bovine corneal opacity and permeability assays.
van der Zalm AJ, Daniel AB, Raabe HA, Choksi N, Flint Silva T, Breeden-Alemi J, O'Dell L, Kleinstreuer NC, Lowit AB, Allen DG, Clippinger AJ. van der Zalm AJ, et al. Among authors: kleinstreuer nc. Cutan Ocul Toxicol. 2024 Mar;43(1):58-68. doi: 10.1080/15569527.2023.2275029. Epub 2023 Oct 31. Cutan Ocul Toxicol. 2024. PMID: 37905558
International regulatory uses of acute systemic toxicity data and integration of new approach methodologies.
Strickland J, Haugabrooks E, Allen DG, Balottin LB, Hirabayashi Y, Kleinstreuer NC, Kojima H, Nishizawa C, Prieto P, Ratzlaff DE, Jeong J, Lee J, Yang Y, Lin P, Sullivan K, Casey W. Strickland J, et al. Among authors: kleinstreuer nc. Crit Rev Toxicol. 2023 Aug;53(7):385-411. doi: 10.1080/10408444.2023.2240852. Epub 2023 Aug 30. Crit Rev Toxicol. 2023. PMID: 37646804 Review.
A database of human predictive patch test data for skin sensitization.
Strickland J, Abedini J, Allen DG, Gordon J, Hull V, Kleinstreuer NC, Ko HS, Matheson J, Thierse HJ, Truax J, Vanselow JT, Herzler M. Strickland J, et al. Among authors: kleinstreuer nc. Arch Toxicol. 2023 Nov;97(11):2825-2837. doi: 10.1007/s00204-023-03530-3. Epub 2023 Aug 24. Arch Toxicol. 2023. PMID: 37615678 Free PMC article. Review.
Parallel evaluation of alternative skin barrier models and excised human skin for dermal absorption studies in vitro.
Salminen AT, Davis KJ, Felton RP, Nischal N, VonTungeln LS, Beland FA, Derr K, Brown PC, Ferrer M, Katz LM, Kleinstreuer NC, Leshin J, Manga P, Sadrieh N, Xia M, Fitzpatrick SC, Camacho L. Salminen AT, et al. Among authors: kleinstreuer nc. Toxicol In Vitro. 2023 Sep;91:105630. doi: 10.1016/j.tiv.2023.105630. Epub 2023 Jun 13. Toxicol In Vitro. 2023. PMID: 37315744
69 results