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Digital Display Precision Predictor: the prototype of a global biomarker model to guide treatments with targeted therapy and predict progression-free survival.
Lazar V, Magidi S, Girard N, Savignoni A, Martini JF, Massimini G, Bresson C, Berger R, Onn A, Raynaud J, Wunder F, Berindan-Neagoe I, Sekacheva M, Braña I, Tabernero J, Felip E, Porgador A, Kleinman C, Batist G, Solomon B, Tsimberidou AM, Soria JC, Rubin E, Kurzrock R, Schilsky RL. Lazar V, et al. Among authors: kleinman c. NPJ Precis Oncol. 2021 Apr 28;5(1):33. doi: 10.1038/s41698-021-00171-6. NPJ Precis Oncol. 2021. PMID: 33911192 Free PMC article.
Copy number and transcriptome alterations associated with metastatic lesion response to treatment in colorectal cancer.
Gambaro K, Marques M, McNamara S, Couetoux du Tertre M, Diaz Z, Hoffert C, Srivastava A, Hébert S, Samson B, Lespérance B, Ko YJ, Dalfen R, St-Hilaire E, Sideris L, Couture F, Burkes R, Harb M, Camlioglu E, Gologan A, Pelsser V, Constantin A, Greenwood CMT, Tejpar S, Kavan P, Kleinman CL, Batist G. Gambaro K, et al. Among authors: kleinman cl. Clin Transl Med. 2021 Apr;11(4):e401. doi: 10.1002/ctm2.401. Clin Transl Med. 2021. PMID: 33931971 Free PMC article.
Gene networks show associations with seed region connectivity.
Forest M, Iturria-Medina Y, Goldman JS, Kleinman CL, Lovato A, Oros Klein K, Evans A, Ciampi A, Labbe A, Greenwood CMT. Forest M, et al. Hum Brain Mapp. 2017 Jun;38(6):3126-3140. doi: 10.1002/hbm.23579. Epub 2017 Mar 21. Hum Brain Mapp. 2017. PMID: 28321948 Free PMC article.
Characterizing temporal genomic heterogeneity in pediatric high-grade gliomas.
Salloum R, McConechy MK, Mikael LG, Fuller C, Drissi R, DeWire M, Nikbakht H, De Jay N, Yang X, Boue D, Chow LML, Finlay JL, Gayden T, Karamchandani J, Hummel TR, Olshefski R, Osorio DS, Stevenson C, Kleinman CL, Majewski J, Fouladi M, Jabado N. Salloum R, et al. Among authors: kleinman cl. Acta Neuropathol Commun. 2017 Oct 30;5(1):78. doi: 10.1186/s40478-017-0479-8. Acta Neuropathol Commun. 2017. PMID: 29084603 Free PMC article.
H3.3K27M Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas.
Pathania M, De Jay N, Maestro N, Harutyunyan AS, Nitarska J, Pahlavan P, Henderson S, Mikael LG, Richard-Londt A, Zhang Y, Costa JR, Hébert S, Khazaei S, Ibrahim NS, Herrero J, Riccio A, Albrecht S, Ketteler R, Brandner S, Kleinman CL, Jabado N, Salomoni P. Pathania M, et al. Cancer Cell. 2017 Nov 13;32(5):684-700.e9. doi: 10.1016/j.ccell.2017.09.014. Epub 2017 Oct 26. Cancer Cell. 2017. PMID: 29107533 Free PMC article.
PRMT5 is essential for B cell development and germinal center dynamics.
Litzler LC, Zahn A, Meli AP, Hébert S, Patenaude AM, Methot SP, Sprumont A, Bois T, Kitamura D, Costantino S, King IL, Kleinman CL, Richard S, Di Noia JM. Litzler LC, et al. Among authors: kleinman cl. Nat Commun. 2019 Jan 3;10(1):22. doi: 10.1038/s41467-018-07884-6. Nat Commun. 2019. PMID: 30604754 Free PMC article.
SWI/SNF-Compromised Cancers Are Susceptible to Bromodomain Inhibitors.
Shorstova T, Marques M, Su J, Johnston J, Kleinman CL, Hamel N, Huang S, Alaoui-Jamali MA, Foulkes WD, Witcher M. Shorstova T, et al. Cancer Res. 2019 May 15;79(10):2761-2774. doi: 10.1158/0008-5472.CAN-18-1545. Epub 2019 Mar 15. Cancer Res. 2019. PMID: 30877105
223 results