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A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy.
Ruas JL, White JP, Rao RR, Kleiner S, Brannan KT, Harrison BC, Greene NP, Wu J, Estall JL, Irving BA, Lanza IR, Rasbach KA, Okutsu M, Nair KS, Yan Z, Leinwand LA, Spiegelman BM. Ruas JL, et al. Among authors: kleiner s. Cell. 2012 Dec 7;151(6):1319-31. doi: 10.1016/j.cell.2012.10.050. Cell. 2012. PMID: 23217713 Free PMC article.
Development of insulin resistance in mice lacking PGC-1α in adipose tissues.
Kleiner S, Mepani RJ, Laznik D, Ye L, Jurczak MJ, Jornayvaz FR, Estall JL, Chatterjee Bhowmick D, Shulman GI, Spiegelman BM. Kleiner S, et al. Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9635-40. doi: 10.1073/pnas.1207287109. Epub 2012 May 29. Proc Natl Acad Sci U S A. 2012. PMID: 22645355 Free PMC article.
IRF4 is a key thermogenic transcriptional partner of PGC-1α.
Kong X, Banks A, Liu T, Kazak L, Rao RR, Cohen P, Wang X, Yu S, Lo JC, Tseng YH, Cypess AM, Xue R, Kleiner S, Kang S, Spiegelman BM, Rosen ED. Kong X, et al. Among authors: kleiner s. Cell. 2014 Jul 3;158(1):69-83. doi: 10.1016/j.cell.2014.04.049. Cell. 2014. PMID: 24995979 Free PMC article.
TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis.
Ye L, Kleiner S, Wu J, Sah R, Gupta RK, Banks AS, Cohen P, Khandekar MJ, Boström P, Mepani RJ, Laznik D, Kamenecka TM, Song X, Liedtke W, Mootha VK, Puigserver P, Griffin PR, Clapham DE, Spiegelman BM. Ye L, et al. Among authors: kleiner s. Cell. 2012 Sep 28;151(1):96-110. doi: 10.1016/j.cell.2012.08.034. Cell. 2012. PMID: 23021218 Free PMC article.
Muscle-secreted neurturin couples myofiber oxidative metabolism and slow motor neuron identity.
Correia JC, Kelahmetoglu Y, Jannig PR, Schweingruber C, Shvaikovskaya D, Zhengye L, Cervenka I, Khan N, Stec M, Oliveira M, Nijssen J, Martínez-Redondo V, Ducommun S, Azzolini M, Lanner JT, Kleiner S, Hedlund E, Ruas JL. Correia JC, et al. Among authors: kleiner s. Cell Metab. 2021 Nov 2;33(11):2215-2230.e8. doi: 10.1016/j.cmet.2021.09.003. Epub 2021 Sep 29. Cell Metab. 2021. PMID: 34592133 Free article.
135 results