Kleiner H - Search Results

1

Reverse Transcription Can Critically Impact the Diagnostic Outcome of BCR::ABL1 Quantitative Real-Time RT-PCR.

Spiess B, Kleiner H, Tarnopolscaia I, Naumann N, Fabarius A, Hofmann WK, Saussele S, Seifarth W. Spiess B, et al. Among authors: kleiner h. Cancers (Basel). 2023 Aug 1;15(15):3914. doi: 10.3390/cancers15153914. Cancers (Basel). 2023. PMID: 37568730 Free PMC article.

2

Gene Expression Pattern of ESPL1, PTTG1 and PTTG1IP Can Potentially Predict Response to TKI First-Line Treatment of Patients with Newly Diagnosed CML.

Christiani E, Naumann N, Weiss C, Spiess B, Kleiner H, Fabarius A, Hofmann WK, Saussele S, Seifarth W. Christiani E, et al. Among authors: kleiner h. Cancers (Basel). 2023 May 8;15(9):2652. doi: 10.3390/cancers15092652. Cancers (Basel). 2023. PMID: 37174118 Free PMC article.

3

c-MYB is a transcriptional regulator of ESPL1/Separase in BCR-ABL-positive chronic myeloid leukemia.

Prinzhorn W, Stehle M, Kleiner H, Ruppenthal S, Müller MC, Hofmann WK, Fabarius A, Seifarth W. Prinzhorn W, et al. Among authors: kleiner h. Biomark Res. 2016 Mar 2;4:5. doi: 10.1186/s40364-016-0059-2. eCollection 2016. Biomark Res. 2016. PMID: 26937281 Free PMC article.

4

Antileukemic Efficacy in Vitro of Talazoparib and APE1 Inhibitor III Combined with Decitabine in Myeloid Malignancies.

Kohl V, Flach J, Naumann N, Brendel S, Kleiner H, Weiss C, Seifarth W, Nowak D, Hofmann WK, Fabarius A, Popp HD. Kohl V, et al. Among authors: kleiner h. Cancers (Basel). 2019 Oct 3;11(10):1493. doi: 10.3390/cancers11101493. Cancers (Basel). 2019. PMID: 31623402 Free PMC article.

5

DNA Damage and DNA Damage Response in Chronic Myeloid Leukemia.

Popp HD, Kohl V, Naumann N, Flach J, Brendel S, Kleiner H, Weiss C, Seifarth W, Saussele S, Hofmann WK, Fabarius A. Popp HD, et al. Among authors: kleiner h. Int J Mol Sci. 2020 Feb 11;21(4):1177. doi: 10.3390/ijms21041177. Int J Mol Sci. 2020. PMID: 32053969 Free PMC article.

6

Separase activity distribution can be a marker of major molecular response and proliferation of CD34⁺ cells in TKI-treated chronic myeloid leukemia patients.

Spiess B, Kleiner H, Flach J, Fabarius A, Saussele S, Hofmann WK, Seifarth W. Spiess B, et al. Among authors: kleiner h. Ann Hematol. 2020 May;99(5):991-1006. doi: 10.1007/s00277-020-04007-4. Epub 2020 Apr 6. Ann Hematol. 2020. PMID: 32253454 Free PMC article. Clinical Trial.

7

Evidence for Recombinant GRP78, CALR, PDIA3 and GPI as Mediators of Genetic Instability in Human CD34+ Cells.

Fabarius A, Samra V, Drews O, Mörz H, Bierbaum M, Darwich A, Weiss C, Brendel S, Kleiner H, Seifarth W, Greffrath W, Hofmann WK, Schmitt CA, Popp HD. Fabarius A, et al. Among authors: kleiner h. Cancers (Basel). 2022 Jun 11;14(12):2883. doi: 10.3390/cancers14122883. Cancers (Basel). 2022. PMID: 35740549 Free PMC article.

8

Clonal Evolution and Blast Crisis Correlate with Enhanced Proteolytic Activity of Separase in BCR-ABL b3a2 Fusion Type CML under Imatinib Therapy.

Haaß W, Kleiner H, Weiß C, Haferlach C, Schlegelberger B, Müller MC, Hehlmann R, Hofmann WK, Fabarius A, Seifarth W; Schweizerische Arbeitsgemeinschaft für Klinische Krebsforschung; German CML Study Group. Haaß W, et al. Among authors: kleiner h. PLoS One. 2015 Jun 18;10(6):e0129648. doi: 10.1371/journal.pone.0129648. eCollection 2015. PLoS One. 2015. PMID: 26087013 Free PMC article.

9

Measurement of separase proteolytic activity in single living cells by a fluorogenic flow cytometry assay.

Haaß W, Kleiner H, Müller MC, Hofmann WK, Fabarius A, Seifarth W. Haaß W, et al. Among authors: kleiner h. PLoS One. 2015 Aug 12;10(8):e0133769. doi: 10.1371/journal.pone.0133769. eCollection 2015. PLoS One. 2015. PMID: 26267133 Free PMC article.

10

Increased separase activity and occurrence of centrosome aberrations concur with transformation of MDS.

Ruppenthal S, Kleiner H, Nolte F, Fabarius A, Hofmann WK, Nowak D, Seifarth W. Ruppenthal S, et al. Among authors: kleiner h. PLoS One. 2018 Jan 25;13(1):e0191734. doi: 10.1371/journal.pone.0191734. eCollection 2018. PLoS One. 2018. PMID: 29370237 Free PMC article.

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