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The role of FXR and TGR5 in reversing and preventing progression of Western diet-induced hepatic steatosis, inflammation, and fibrosis in mice.
Wang XX, Xie C, Libby AE, Ranjit S, Levi J, Myakala K, Bhasin K, Jones BA, Orlicky DJ, Takahashi S, Dvornikov A, Kleiner DE, Hewitt SM, Adorini L, Kopp JB, Krausz KW, Rosenberg A, McManaman JL, Robertson CE, Ir D, Frank DN, Luo Y, Gonzalez FJ, Gratton E, Levi M. Wang XX, et al. Among authors: kleiner de. J Biol Chem. 2022 Nov;298(11):102530. doi: 10.1016/j.jbc.2022.102530. Epub 2022 Oct 7. J Biol Chem. 2022. PMID: 36209823 Free PMC article.
Microvascular inflammation in renal allograft biopsies assessed by endothelial and leukocyte co-immunostain: a retrospective study on reproducibility and clinical/prognostic correlates.
Delsante M, Maggiore U, Levi J, Kleiner DE, Jackson AM, Arend LJ, Hewitt SM, Carter-Monroe N, Bagnasco SM, Rosenberg AZ. Delsante M, et al. Among authors: kleiner de. Transpl Int. 2019 Mar;32(3):300-312. doi: 10.1111/tri.13371. Epub 2018 Dec 11. Transpl Int. 2019. PMID: 30395360 Free PMC article.
Biophysical and functional characterization of full-length, recombinant human tissue inhibitor of metalloproteinases-2 (TIMP-2) produced in Escherichia coli. Comparison of wild type and amino-terminal alanine appended variant with implications for the mechanism of TIMP functions.
Wingfield PT, Sax JK, Stahl SJ, Kaufman J, Palmer I, Chung V, Corcoran ML, Kleiner DE, Stetler-Stevenson WG. Wingfield PT, et al. Among authors: kleiner de. J Biol Chem. 1999 Jul 23;274(30):21362-8. doi: 10.1074/jbc.274.30.21362. J Biol Chem. 1999. PMID: 10409697 Free article.
Progression of fibrosis in chronic hepatitis C.
Ghany MG, Kleiner DE, Alter H, Doo E, Khokar F, Promrat K, Herion D, Park Y, Liang TJ, Hoofnagle JH. Ghany MG, et al. Among authors: kleiner de. Gastroenterology. 2003 Jan;124(1):97-104. doi: 10.1053/gast.2003.50018. Gastroenterology. 2003. PMID: 12512034
A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis.
Promrat K, Lutchman G, Uwaifo GI, Freedman RJ, Soza A, Heller T, Doo E, Ghany M, Premkumar A, Park Y, Liang TJ, Yanovski JA, Kleiner DE, Hoofnagle JH. Promrat K, et al. Among authors: kleiner de. Hepatology. 2004 Jan;39(1):188-96. doi: 10.1002/hep.20012. Hepatology. 2004. PMID: 14752837 Clinical Trial.
513 results