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Page 1
Griffithsin carrageenan fast dissolving inserts prevent SHIV HSV-2 and HPV infections in vivo.
Derby N, Lal M, Aravantinou M, Kizima L, Barnable P, Rodriguez A, Lai M, Wesenberg A, Ugaonkar S, Levendosky K, Mizenina O, Kleinbeck K, Lifson JD, Peet MM, Lloyd Z, Benson M, Heneine W, O'Keefe BR, Robbiani M, Martinelli E, Grasperge B, Blanchard J, Gettie A, Teleshova N, Fernández-Romero JA, Zydowsky TM. Derby N, et al. Among authors: kleinbeck k. Nat Commun. 2018 Sep 24;9(1):3881. doi: 10.1038/s41467-018-06349-0. Nat Commun. 2018. PMID: 30250170 Free PMC article.
In vitro and in vivo evaluation of two carrageenan-based formulations to prevent HPV acquisition.
Rodríguez A, Kleinbeck K, Mizenina O, Kizima L, Levendosky K, Jean-Pierre N, Villegas G, Ford BE, Cooney ML, Teleshova N, Robbiani M, Herold BC, Zydowsky T, Fernández Romero JA. Rodríguez A, et al. Among authors: kleinbeck k. Antiviral Res. 2014 Aug;108:88-93. doi: 10.1016/j.antiviral.2014.05.018. Epub 2014 Jun 5. Antiviral Res. 2014. PMID: 24909570 Free PMC article.
Short communication: a repeated simian human immunodeficiency virus reverse transcriptase/herpes simplex virus type 2 cochallenge macaque model for the evaluation of microbicides.
Kenney J, Derby N, Aravantinou M, Kleinbeck K, Frank I, Gettie A, Grasperge B, Blanchard J, Piatak M Jr, Lifson JD, Zydowsky TM, Robbiani M. Kenney J, et al. Among authors: kleinbeck k. AIDS Res Hum Retroviruses. 2014 Nov;30(11):1117-24. doi: 10.1089/aid.2014.0207. AIDS Res Hum Retroviruses. 2014. PMID: 25354024 Free PMC article.
Griffithsin and Carrageenan Combination To Target Herpes Simplex Virus 2 and Human Papillomavirus.
Levendosky K, Mizenina O, Martinelli E, Jean-Pierre N, Kizima L, Rodriguez A, Kleinbeck K, Bonnaire T, Robbiani M, Zydowsky TM, O'Keefe BR, Fernández-Romero JA. Levendosky K, et al. Among authors: kleinbeck k. Antimicrob Agents Chemother. 2015 Dec;59(12):7290-8. doi: 10.1128/AAC.01816-15. Epub 2015 Sep 14. Antimicrob Agents Chemother. 2015. PMID: 26369967 Free PMC article.
Results of a phase 1, randomized, placebo-controlled first-in-human trial of griffithsin formulated in a carrageenan vaginal gel.
Teleshova N, Keller MJ, Fernández Romero JA, Friedland BA, Creasy GW, Plagianos MG, Ray L, Barnable P, Kizima L, Rodriguez A, Cornejal N, Melo C, Cruz Rodriguez G, Mukhopadhyay S, Calenda G, Sinkar SU, Bonnaire T, Wesenberg A, Zhang S, Kleinbeck K, Palmer K, Alami M, O'Keefe BR, Gillevet P, Hur H, Liang Y, Santone G, Fichorova RN, Kalir T, Zydowsky TM. Teleshova N, et al. Among authors: kleinbeck k. PLoS One. 2022 Jan 20;17(1):e0261775. doi: 10.1371/journal.pone.0261775. eCollection 2022. PLoS One. 2022. PMID: 35051209 Free PMC article. Clinical Trial.
First-in-Human Trial of MIV-150 and Zinc Acetate Coformulated in a Carrageenan Gel: Safety, Pharmacokinetics, Acceptability, Adherence, and Pharmacodynamics.
Friedland BA, Hoesley CJ, Plagianos M, Hoskin E, Zhang S, Teleshova N, Alami M, Novak L, Kleinbeck KR, Katzen LL, Zydowsky TM, Fernández-Romero JA, Creasy GW. Friedland BA, et al. Among authors: kleinbeck kr. J Acquir Immune Defic Syndr. 2016 Dec 15;73(5):489-496. doi: 10.1097/QAI.0000000000001136. J Acquir Immune Defic Syndr. 2016. PMID: 27437826 Free PMC article. Clinical Trial.
A Small Molecule, Which Competes with MAdCAM-1, Activates Integrin α4β7 and Fails to Prevent Mucosal Transmission of SHIV-SF162P3.
Arrode-Brusés G, Goode D, Kleinbeck K, Wilk J, Frank I, Byrareddy S, Arthos J, Grasperge B, Blanchard J, Zydowsky T, Gettie A, Martinelli E. Arrode-Brusés G, et al. Among authors: kleinbeck k. PLoS Pathog. 2016 Jun 27;12(6):e1005720. doi: 10.1371/journal.ppat.1005720. eCollection 2016 Jun. PLoS Pathog. 2016. PMID: 27348748 Free PMC article.
In Vitro Exposure to PC-1005 and Cervicovaginal Lavage Fluid from Women Vaginally Administered PC-1005 Inhibits HIV-1 and HSV-2 Infection in Human Cervical Mucosa.
Villegas G, Calenda G, Zhang S, Mizenina O, Kleinbeck K, Cooney ML, Hoesley CJ, Creasy GW, Friedland B, Fernández-Romero JA, Zydowsky TM, Teleshova N. Villegas G, et al. Among authors: kleinbeck k. Antimicrob Agents Chemother. 2016 Aug 22;60(9):5459-66. doi: 10.1128/AAC.00392-16. Print 2016 Sep. Antimicrob Agents Chemother. 2016. PMID: 27381393 Free PMC article. Clinical Trial.
Correction: A Small Molecule, Which Competes with MAdCAM-1, Activates Integrin α4β7 and Fails to Prevent Mucosal Transmission of SHIV-SF162P3.
Arrode-Brusés G, Goode D, Kleinbeck K, Wilk J, Frank I, Byrareddy S, Arthos J, Grasperge B, Blanchard J, Zydowsky T, Gettie A, Martinelli E. Arrode-Brusés G, et al. Among authors: kleinbeck k. PLoS Pathog. 2016 Jul 14;12(7):e1005781. doi: 10.1371/journal.ppat.1005781. eCollection 2016 Jul. PLoS Pathog. 2016. PMID: 27415435 Free PMC article.
In vitro drug release, mechanical performance and stability testing of a custom silicone elastomer vaginal ring releasing dapivirine and levonorgestrel.
Murphy DJ, Dallal Bashi YH, McCoy CF, Boyd P, Brown L, Martin F, McMullen N, Kleinbeck K, Dangi B, Spence P, Hansraj B, Devlin B, Malcolm RK. Murphy DJ, et al. Among authors: kleinbeck k. Int J Pharm X. 2022 Jan 25;4:100112. doi: 10.1016/j.ijpx.2022.100112. eCollection 2022 Dec. Int J Pharm X. 2022. PMID: 35128382 Free PMC article.
25 results