Kleinau G - Search Results

1

Angiotensin and Endothelin Receptor Structures With Implications for Signaling Regulation and Pharmacological Targeting.

Speck D, Kleinau G, Szczepek M, Kwiatkowski D, Catar R, Philippe A, Scheerer P. Speck D, et al. Among authors: kleinau g. Front Endocrinol (Lausanne). 2022 Apr 19;13:880002. doi: 10.3389/fendo.2022.880002. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 35518926 Free PMC article. Review.

2

A hydrophobic cluster in the center of the third extracellular loop is important for thyrotropin receptor signaling.

Claus M, Jaeschke H, Kleinau G, Neumann S, Krause G, Paschke R. Claus M, et al. Among authors: kleinau g. Endocrinology. 2005 Dec;146(12):5197-203. doi: 10.1210/en.2005-0713. Epub 2005 Sep 8. Endocrinology. 2005. PMID: 16150909

3

Inhibition of melanocortin-4 receptor dimerization by substitutions in intracellular loop 2.

Piechowski CL, Rediger A, Lagemann C, Mühlhaus J, Müller A, Pratzka J, Tarnow P, Grüters A, Krude H, Kleinau G, Biebermann H. Piechowski CL, et al. Among authors: kleinau g. J Mol Endocrinol. 2013 Jun 29;51(1):109-18. doi: 10.1530/JME-13-0061. Print 2013. J Mol Endocrinol. 2013. PMID: 23674133

4

Oligomerization of GPCRs involved in endocrine regulation.

Kleinau G, Müller A, Biebermann H. Kleinau G, et al. J Mol Endocrinol. 2016 Jul;57(1):R59-80. doi: 10.1530/JME-16-0049. Epub 2016 May 5. J Mol Endocrinol. 2016. PMID: 27151573 Review.

5

Ring Finger Protein 11 Inhibits Melanocortin 3 and 4 Receptor Signaling.

Müller A, Niederstadt L, Jonas W, Yi CX, Meyer F, Wiedmer P, Fischer J, Grötzinger C, Schürmann A, Tschöp M, Kleinau G, Grüters A, Krude H, Biebermann H. Müller A, et al. Among authors: kleinau g. Front Endocrinol (Lausanne). 2016 Aug 8;7:109. doi: 10.3389/fendo.2016.00109. eCollection 2016. Front Endocrinol (Lausanne). 2016. PMID: 27551276 Free PMC article.

6

Insights into Basal Signaling Regulation, Oligomerization, and Structural Organization of the Human G-Protein Coupled Receptor 83.

Müller A, Berkmann JC, Scheerer P, Biebermann H, Kleinau G. Müller A, et al. Among authors: kleinau g. PLoS One. 2016 Dec 9;11(12):e0168260. doi: 10.1371/journal.pone.0168260. eCollection 2016. PLoS One. 2016. PMID: 27936173 Free PMC article.

7

Structural-Functional Features of the Thyrotropin Receptor: A Class A G-Protein-Coupled Receptor at Work.

Kleinau G, Worth CL, Kreuchwig A, Biebermann H, Marcinkowski P, Scheerer P, Krause G. Kleinau G, et al. Front Endocrinol (Lausanne). 2017 Apr 24;8:86. doi: 10.3389/fendo.2017.00086. eCollection 2017. Front Endocrinol (Lausanne). 2017. PMID: 28484426 Free PMC article. Review.

8

The Trace Amine-Associated Receptor 1 Agonist 3-Iodothyronamine Induces Biased Signaling at the Serotonin 1b Receptor.

Bräunig J, Dinter J, Höfig CS, Paisdzior S, Szczepek M, Scheerer P, Rosowski M, Mittag J, Kleinau G, Biebermann H. Bräunig J, et al. Among authors: kleinau g. Front Pharmacol. 2018 Mar 12;9:222. doi: 10.3389/fphar.2018.00222. eCollection 2018. Front Pharmacol. 2018. PMID: 29593543 Free PMC article.

9

MC4R agonism promotes durable weight loss in patients with leptin receptor deficiency.

Clément K, Biebermann H, Farooqi IS, Van der Ploeg L, Wolters B, Poitou C, Puder L, Fiedorek F, Gottesdiener K, Kleinau G, Heyder N, Scheerer P, Blume-Peytavi U, Jahnke I, Sharma S, Mokrosinski J, Wiegand S, Müller A, Weiß K, Mai K, Spranger J, Grüters A, Blankenstein O, Krude H, Kühnen P. Clément K, et al. Among authors: kleinau g. Nat Med. 2018 May;24(5):551-555. doi: 10.1038/s41591-018-0015-9. Epub 2018 May 7. Nat Med. 2018. PMID: 29736023 Clinical Trial.

10

Binding, Thermodynamics, and Selectivity of a Non-peptide Antagonist to the Melanocortin-4 Receptor.

Saleh N, Kleinau G, Heyder N, Clark T, Hildebrand PW, Scheerer P. Saleh N, et al. Among authors: kleinau g. Front Pharmacol. 2018 Jun 1;9:560. doi: 10.3389/fphar.2018.00560. eCollection 2018. Front Pharmacol. 2018. PMID: 29910730 Free PMC article.

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