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Harnessing synthetic biology to engineer organoids and tissues.
Trentesaux C, Yamada T, Klein OD, Lim WA. Trentesaux C, et al. Among authors: klein od. Cell Stem Cell. 2023 Jan 5;30(1):10-19. doi: 10.1016/j.stem.2022.12.013. Cell Stem Cell. 2023. PMID: 36608674 Free article. Review.
A DLG1-ARHGAP31-CDC42 axis is essential for the intestinal stem cell response to fluctuating niche Wnt signaling.
Castillo-Azofeifa D, Wald T, Reyes EA, Gallagher A, Schanin J, Vlachos S, Lamarche-Vane N, Bomidi C, Blutt S, Estes MK, Nystul T, Klein OD. Castillo-Azofeifa D, et al. Among authors: klein od. Cell Stem Cell. 2023 Feb 2;30(2):188-206.e6. doi: 10.1016/j.stem.2022.12.008. Epub 2023 Jan 13. Cell Stem Cell. 2023. PMID: 36640764 Free PMC article.
EPIREGULIN creates a developmental niche for spatially organized human intestinal enteroids.
Childs CJ, Holloway EM, Sweet CW, Tsai YH, Wu A, Vallie A, Eiken MK, Capeling MM, Zwick RK, Palikuqi B, Trentesaux C, Wu JH, Pellón-Cardenas O, Zhang CJ, Glass I, Loebel C, Yu Q, Camp JG, Sexton JZ, Klein OD, Verzi MP, Spence JR. Childs CJ, et al. Among authors: klein od. JCI Insight. 2023 Mar 22;8(6):e165566. doi: 10.1172/jci.insight.165566. JCI Insight. 2023. PMID: 36821371 Free PMC article.
YAP-Driven Malignant Reprogramming of Epithelial Stem Cells at Single Cell Resolution.
Gutkind JS, Faraji F, Ramirez S, Clubb L, Sato K, Quiroz PA, Galloway W, Mikulski Z, Hoang T, Medetgul-Ernar K, Marangoni P, Jones K, Officer A, Molinolo A, Kim K, Sakaguchi K, Califano J, Smith Q, Klein O, Tamayo P. Gutkind JS, et al. Res Sq [Preprint]. 2023 Oct 27:rs.3.rs-3426301. doi: 10.21203/rs.3.rs-3426301/v1. Res Sq. 2023. PMID: 37961717 Free PMC article. Preprint.
Patterning and folding of intestinal villi by active mesenchymal dewetting.
Huycke TR, Miyazaki H, Häkkinen TJ, Srivastava V, Barruet E, McGinnis CS, Kalantari A, Cornwall-Scoones J, Vaka D, Zhu Q, Jo H, DeGrado WF, Thomson M, Garikipati K, Boffelli D, Klein OD, Gartner ZJ. Huycke TR, et al. Among authors: klein od. bioRxiv [Preprint]. 2023 Aug 15:2023.06.25.546328. doi: 10.1101/2023.06.25.546328. bioRxiv. 2023. PMID: 37425793 Free PMC article. Preprint.
193 results