Klein L - Search Results

1

Reverse TCR repertoire evolution toward dominant low-affinity clones during chronic CMV infection.

Schober K, Voit F, Grassmann S, Müller TR, Eggert J, Jarosch S, Weißbrich B, Hoffmann P, Borkner L, Nio E, Fanchi L, Clouser CR, Radhakrishnan A, Mihatsch L, Lückemeier P, Leube J, Dössinger G, Klein L, Neuenhahn M, Oduro JD, Cicin-Sain L, Buchholz VR, Busch DH. Schober K, et al. Among authors: klein l. Nat Immunol. 2020 Apr;21(4):434-441. doi: 10.1038/s41590-020-0628-2. Epub 2020 Mar 16. Nat Immunol. 2020. PMID: 32205883

2

Macroautophagy, endogenous MHC II loading and T cell selection: the benefits of breaking the rules.

Nedjic J, Aichinger M, Mizushima N, Klein L. Nedjic J, et al. Among authors: klein l. Curr Opin Immunol. 2009 Feb;21(1):92-7. doi: 10.1016/j.coi.2009.01.013. Epub 2009 Feb 24. Curr Opin Immunol. 2009. PMID: 19246181 Review.

3

Antigen presentation in the thymus for positive selection and central tolerance induction.

Klein L, Hinterberger M, Wirnsberger G, Kyewski B. Klein L, et al. Nat Rev Immunol. 2009 Dec;9(12):833-44. doi: 10.1038/nri2669. Nat Rev Immunol. 2009. PMID: 19935803 Review.

4

Autonomous role of medullary thymic epithelial cells in central CD4(+) T cell tolerance.

Hinterberger M, Aichinger M, Prazeres da Costa O, Voehringer D, Hoffmann R, Klein L. Hinterberger M, et al. Among authors: klein l. Nat Immunol. 2010 Jun;11(6):512-9. doi: 10.1038/ni.1874. Epub 2010 May 2. Nat Immunol. 2010. PMID: 20431619 Free article.

5

Regulatory T-cell differentiation versus clonal deletion of autoreactive thymocytes.

Wirnsberger G, Hinterberger M, Klein L. Wirnsberger G, et al. Among authors: klein l. Immunol Cell Biol. 2011 Jan;89(1):45-53. doi: 10.1038/icb.2010.123. Epub 2010 Nov 2. Immunol Cell Biol. 2011. PMID: 21042335 Review.

6

Positive and negative selection of the T cell repertoire: what thymocytes see (and don't see).

Klein L, Kyewski B, Allen PM, Hogquist KA. Klein L, et al. Nat Rev Immunol. 2014 Jun;14(6):377-91. doi: 10.1038/nri3667. Epub 2014 May 16. Nat Rev Immunol. 2014. PMID: 24830344 Free PMC article. Review.

7

Central CD4⁺ T cell tolerance: deletion versus regulatory T cell differentiation.

Klein L, Robey EA, Hsieh CS. Klein L, et al. Nat Rev Immunol. 2019 Jan;19(1):7-18. doi: 10.1038/s41577-018-0083-6. Nat Rev Immunol. 2019. PMID: 30420705 Review.

8

B cells latently infected with murine gammaherpesvirus 68 (MHV-68) are present in the mouse thymus-A step toward immune evasion?

Yamano T, Steinert M, Steer B, Klein L, Hammerschmidt W, Adler H. Yamano T, et al. Among authors: klein l. Eur J Immunol. 2019 Feb;49(2):351-352. doi: 10.1002/eji.201847886. Epub 2018 Dec 10. Eur J Immunol. 2019. PMID: 30488950 Free article.

9

Inventories of naive and tolerant mouse CD4 T cell repertoires reveal a hierarchy of deleted and diverted T cell receptors.

Hassler T, Urmann E, Teschner S, Federle C, Dileepan T, Schober K, Jenkins MK, Busch DH, Hinterberger M, Klein L. Hassler T, et al. Among authors: klein l. Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18537-18543. doi: 10.1073/pnas.1907615116. Epub 2019 Aug 26. Proc Natl Acad Sci U S A. 2019. PMID: 31451631 Free PMC article.

10

B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4.

Afzali AM, Nirschl L, Sie C, Pfaller M, Ulianov O, Hassler T, Federle C, Petrozziello E, Kalluri SR, Chen HH, Tyystjärvi S, Muschaweckh A, Lammens K, Delbridge C, Büttner A, Steiger K, Seyhan G, Ottersen OP, Öllinger R, Rad R, Jarosch S, Straub A, Mühlbauer A, Grassmann S, Hemmer B, Böttcher JP, Wagner I, Kreutzfeldt M, Merkler D, Pardàs IB, Schmidt Supprian M, Buchholz VR, Heink S, Busch DH, Klein L, Korn T. Afzali AM, et al. Among authors: klein l. Nature. 2024 Mar;627(8003):407-415. doi: 10.1038/s41586-024-07079-8. Epub 2024 Feb 21. Nature. 2024. PMID: 38383779 Free PMC article.

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