Klein K - Search Results

1

Consequences of Amyloid-β Deficiency for the Liver.

Buniatian GH, Schwinghammer U, Tremmel R, Cynis H, Weiss TS, Weiskirchen R, Lauschke VM, Youhanna S, Ramos I, Valcarcel M, Seferyan T, Rahfeld JU, Rieckmann V, Klein K, Buadze M, Weber V, Kolak V, Gebhardt R, Friedman SL, Müller UC, Schwab M, Danielyan L. Buniatian GH, et al. Among authors: klein k. Adv Sci (Weinh). 2024 Mar 2:e2307734. doi: 10.1002/advs.202307734. Online ahead of print. Adv Sci (Weinh). 2024. PMID: 38430535

2

Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver.

Lang T, Klein K, Fischer J, Nüssler AK, Neuhaus P, Hofmann U, Eichelbaum M, Schwab M, Zanger UM. Lang T, et al. Among authors: klein k. Pharmacogenetics. 2001 Jul;11(5):399-415. doi: 10.1097/00008571-200107000-00004. Pharmacogenetics. 2001. PMID: 11470993

3

Discriminative quantification of cytochrome P4502D6 and 2D7/8 pseudogene expression by TaqMan real-time reverse transcriptase polymerase chain reaction.

Endrizzi K, Fischer J, Klein K, Schwab M, Nüssler A, Neuhaus P, Eichelbaum M, Zanger UM. Endrizzi K, et al. Among authors: klein k. Anal Biochem. 2002 Jan 15;300(2):121-31. doi: 10.1006/abio.2001.5453. Anal Biochem. 2002. PMID: 11779102

4

Genetic polymorphisms of glutathione S-transferase A1, the major glutathione S-transferase in human liver: consequences for enzyme expression and busulfan conjugation.

Bredschneider M, Klein K, Mürdter TE, Marx C, Eichelbaum M, Nüssler AK, Neuhaus P, Zanger UM, Schwab M. Bredschneider M, et al. Among authors: klein k. Clin Pharmacol Ther. 2002 Jun;71(6):479-87. doi: 10.1067/mcp.2002.124518. Clin Pharmacol Ther. 2002. PMID: 12087351

5

Sex is a major determinant of CYP3A4 expression in human liver.

Wolbold R, Klein K, Burk O, Nüssler AK, Neuhaus P, Eichelbaum M, Schwab M, Zanger UM. Wolbold R, et al. Among authors: klein k. Hepatology. 2003 Oct;38(4):978-88. doi: 10.1053/jhep.2003.50393. Hepatology. 2003. PMID: 14512885

6

A novel intronic mutation, 2988G>A, with high predictivity for impaired function of cytochrome P450 2D6 in white subjects.

Raimundo S, Toscano C, Klein K, Fischer J, Griese EU, Eichelbaum M, Schwab M, Zanger UM. Raimundo S, et al. Among authors: klein k. Clin Pharmacol Ther. 2004 Aug;76(2):128-38. doi: 10.1016/j.clpt.2004.04.009. Clin Pharmacol Ther. 2004. PMID: 15289790

7

Genetic variability of CYP2B6 in populations of African and Asian origin: allele frequencies, novel functional variants, and possible implications for anti-HIV therapy with efavirenz.

Klein K, Lang T, Saussele T, Barbosa-Sicard E, Schunck WH, Eichelbaum M, Schwab M, Zanger UM. Klein K, et al. Pharmacogenet Genomics. 2005 Dec;15(12):861-73. doi: 10.1097/01213011-200512000-00004. Pharmacogenet Genomics. 2005. PMID: 16272958

8

A silent mutation (2939G>A, exon 6; CYP2D6*59) leading to impaired expression and function of CYP2D6.

Toscano C, Raimundo S, Klein K, Eichelbaum M, Schwab M, Zanger UM. Toscano C, et al. Among authors: klein k. Pharmacogenet Genomics. 2006 Oct;16(10):767-70. doi: 10.1097/01.fpc.0000236331.03681.24. Pharmacogenet Genomics. 2006. PMID: 17001296

9

MALDI-TOF mass spectrometry for multiplex genotyping of CYP2B6 single-nucleotide polymorphisms.

Blievernicht JK, Schaeffeler E, Klein K, Eichelbaum M, Schwab M, Zanger UM. Blievernicht JK, et al. Among authors: klein k. Clin Chem. 2007 Jan;53(1):24-33. doi: 10.1373/clinchem.2006.074856. Epub 2006 Nov 2. Clin Chem. 2007. PMID: 17082249

10

Polymorphic CYP2B6: molecular mechanisms and emerging clinical significance.

Zanger UM, Klein K, Saussele T, Blievernicht J, Hofmann MH, Schwab M. Zanger UM, et al. Among authors: klein k. Pharmacogenomics. 2007 Jul;8(7):743-59. doi: 10.2217/14622416.8.7.743. Pharmacogenomics. 2007. PMID: 17638512

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