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Loss of JAK1 Drives Innate Immune Deficiency.
Witalisz-Siepracka A, Klein K, Prinz D, Leidenfrost N, Schabbauer G, Dohnal A, Sexl V. Witalisz-Siepracka A, et al. Among authors: klein k. Front Immunol. 2019 Jan 8;9:3108. doi: 10.3389/fimmu.2018.03108. eCollection 2018. Front Immunol. 2019. PMID: 30671064 Free PMC article.
Human signal transducer and activator of transcription 5b (STAT5b) mutation causes dysregulated human natural killer cell maturation and impaired lytic function.
Vargas-Hernández A, Witalisz-Siepracka A, Prchal-Murphy M, Klein K, Mahapatra S, Al-Herz W, Mace EM, Carisey AF, Orange JS, Sexl V, Forbes LR. Vargas-Hernández A, et al. Among authors: klein k. J Allergy Clin Immunol. 2020 Jan;145(1):345-357.e9. doi: 10.1016/j.jaci.2019.09.016. Epub 2019 Oct 7. J Allergy Clin Immunol. 2020. PMID: 31600547 Free PMC article.
STAT1 Isoforms Differentially Regulate NK Cell Maturation and Anti-tumor Activity.
Meissl K, Simonović N, Amenitsch L, Witalisz-Siepracka A, Klein K, Lassnig C, Puga A, Vogl C, Poelzl A, Bosmann M, Dohnal A, Sexl V, Müller M, Strobl B. Meissl K, et al. Among authors: klein k. Front Immunol. 2020 Sep 11;11:2189. doi: 10.3389/fimmu.2020.02189. eCollection 2020. Front Immunol. 2020. PMID: 33042133 Free PMC article.
The Multifaceted Role of STAT3 in NK-Cell Tumor Surveillance.
Witalisz-Siepracka A, Klein K, Zdársky B, Stoiber D. Witalisz-Siepracka A, et al. Among authors: klein k. Front Immunol. 2022 Jul 5;13:947568. doi: 10.3389/fimmu.2022.947568. eCollection 2022. Front Immunol. 2022. PMID: 35865518 Free PMC article. Review.
A lineage-specific STAT5BN642H mouse model to study NK-cell leukemia.
Klein K, Kollmann S, Hiesinger A, List J, Kendler J, Klampfl T, Randhawa M, Trifinopoulos J, Maurer B, Grausenburger R, Bertram CA, Moriggl RH, Rülicke T, Mullighan CG, Witalisz-Siepracka A, Walter W, Hoermann G, Sexl V, Gotthardt D. Klein K, et al. Blood. 2024 Mar 18:blood.2023022655. doi: 10.1182/blood.2023022655. Online ahead of print. Blood. 2024. PMID: 38498036 Free article.
2,109 results