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Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging.
Cell. 2017 Mar 23;169(1):132-147.e16. doi: 10.1016/j.cell.2017.02.031.
Cell. 2017.
PMID: 28340339
Free PMC article.
Fasting induces a highly resilient deep quiescent state in muscle stem cells via ketone body signaling.
Benjamin DI, Both P, Benjamin JS, Nutter CW, Tan JH, Kang J, Machado LA, Klein JDD, de Morree A, Kim S, Liu L, Dulay H, Feraboli L, Louie SM, Nomura DK, Rando TA.
Benjamin DI, et al. Among authors: klein jdd.
Cell Metab. 2022 Jun 7;34(6):902-918.e6. doi: 10.1016/j.cmet.2022.04.012. Epub 2022 May 17.
Cell Metab. 2022.
PMID: 35584694
Free PMC article.
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Death-seq identifies regulators of cell death and senolytic therapies.
Colville A, Liu JY, Rodriguez-Mateo C, Thomas S, Ishak HD, Zhou R, Klein JDD, Morgens DW, Goshayeshi A, Salvi JS, Yao D, Spees K, Dixon SJ, Liu C, Rhee JW, Lai C, Wu JC, Bassik MC, Rando TA.
Colville A, et al. Among authors: klein jdd.
Cell Metab. 2023 Oct 3;35(10):1814-1829.e6. doi: 10.1016/j.cmet.2023.08.008. Epub 2023 Sep 11.
Cell Metab. 2023.
PMID: 37699398
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Alternative polyadenylation of Pax3 controls muscle stem cell fate and muscle function.
de Morree A, Klein JDD, Gan Q, Farup J, Urtasun A, Kanugovi A, Bilen B, van Velthoven CTJ, Quarta M, Rando TA.
de Morree A, et al. Among authors: klein jdd.
Science. 2019 Nov 8;366(6466):734-738. doi: 10.1126/science.aax1694.
Science. 2019.
PMID: 31699935
Free PMC article.
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Staufen1 inhibits MyoD translation to actively maintain muscle stem cell quiescence.
de Morrée A, van Velthoven CTJ, Gan Q, Salvi JS, Klein JDD, Akimenko I, Quarta M, Biressi S, Rando TA.
de Morrée A, et al. Among authors: klein jdd.
Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):E8996-E9005. doi: 10.1073/pnas.1708725114. Epub 2017 Oct 9.
Proc Natl Acad Sci U S A. 2017.
PMID: 29073096
Free PMC article.
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