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Cysteinyl leukotrienes and acetylcholine are biliary tuft cell cotransmitters.
Keshavarz M, Faraj Tabrizi S, Ruppert AL, Pfeil U, Schreiber Y, Klein J, Brandenburger I, Lochnit G, Bhushan S, Perniss A, Deckmann K, Hartmann P, Meiners M, Mermer P, Rafiq A, Winterberg S, Papadakis T, Thomas D, Angioni C, Oberwinkler J, Chubanov V, Gudermann T, Gärtner U, Offermanns S, Schütz B, Kummer W. Keshavarz M, et al. Among authors: klein j. Sci Immunol. 2022 Mar 4;7(69):eabf6734. doi: 10.1126/sciimmunol.abf6734. Epub 2022 Mar 4. Sci Immunol. 2022. PMID: 35245090
Bitter triggers acetylcholine release from polymodal urethral chemosensory cells and bladder reflexes.
Deckmann K, Filipski K, Krasteva-Christ G, Fronius M, Althaus M, Rafiq A, Papadakis T, Renno L, Jurastow I, Wessels L, Wolff M, Schütz B, Weihe E, Chubanov V, Gudermann T, Klein J, Bschleipfer T, Kummer W. Deckmann K, et al. Among authors: klein j. Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):8287-92. doi: 10.1073/pnas.1402436111. Epub 2014 May 19. Proc Natl Acad Sci U S A. 2014. PMID: 24843119 Free PMC article.
Phosphocholine-Modified Macromolecules and Canonical Nicotinic Agonists Inhibit ATP-Induced IL-1β Release.
Hecker A, Küllmar M, Wilker S, Richter K, Zakrzewicz A, Atanasova S, Mathes V, Timm T, Lerner S, Klein J, Kaufmann A, Bauer S, Padberg W, Kummer W, Janciauskiene S, Fronius M, Schweda EK, Lochnit G, Grau V. Hecker A, et al. Among authors: klein j. J Immunol. 2015 Sep 1;195(5):2325-34. doi: 10.4049/jimmunol.1400974. Epub 2015 Jul 22. J Immunol. 2015. PMID: 26202987
Chemosensory Cell-Derived Acetylcholine Drives Tracheal Mucociliary Clearance in Response to Virulence-Associated Formyl Peptides.
Perniss A, Liu S, Boonen B, Keshavarz M, Ruppert AL, Timm T, Pfeil U, Soultanova A, Kusumakshi S, Delventhal L, Aydin Ö, Pyrski M, Deckmann K, Hain T, Schmidt N, Ewers C, Günther A, Lochnit G, Chubanov V, Gudermann T, Oberwinkler J, Klein J, Mikoshiba K, Leinders-Zufall T, Offermanns S, Schütz B, Boehm U, Zufall F, Bufe B, Kummer W. Perniss A, et al. Among authors: klein j. Immunity. 2020 Apr 14;52(4):683-699.e11. doi: 10.1016/j.immuni.2020.03.005. Immunity. 2020. PMID: 32294408 Free article.
Alpha-1 Antitrypsin Inhibits ATP-Mediated Release of Interleukin-1β via CD36 and Nicotinic Acetylcholine Receptors.
Siebers K, Fink B, Zakrzewicz A, Agné A, Richter K, Konzok S, Hecker A, Zukunft S, Küllmar M, Klein J, McIntosh JM, Timm T, Sewald K, Padberg W, Aggarwal N, Chamulitrat W, Santoso S, Xia W, Janciauskiene S, Grau V. Siebers K, et al. Among authors: klein j. Front Immunol. 2018 Apr 25;9:877. doi: 10.3389/fimmu.2018.00877. eCollection 2018. Front Immunol. 2018. PMID: 29922281 Free PMC article.
5,536 results