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Cell-type-specific Alzheimer's disease polygenic risk scores are associated with distinct disease processes in Alzheimer's disease.
Yang HS, Teng L, Kang D, Menon V, Ge T, Finucane HK, Schultz AP, Properzi M, Klein HU, Chibnik LB, Schneider JA, Bennett DA, Hohman TJ, Mayeux RP, Johnson KA, De Jager PL, Sperling RA. Yang HS, et al. Among authors: klein hu. medRxiv [Preprint]. 2023 Jun 5:2023.06.01.23290850. doi: 10.1101/2023.06.01.23290850. medRxiv. 2023. PMID: 37333223 Free PMC article. Updated. Preprint.
Cell-type-specific regulation of APOE levels in human neurons by the Alzheimer's disease risk gene SORL1.
Lee H, Aylward AJ, Pearse RV, Hsieh YC, Augur ZM, Benoit CR, Chou V, Knupp A, Pan C, Goberdhan S, Duong DM, Seyfried NT, Bennett DA, Klein HU, De Jager PL, Menon V, Young JE, Young-Pearse TL. Lee H, et al. Among authors: klein hu. bioRxiv [Preprint]. 2023 Feb 25:2023.02.25.530017. doi: 10.1101/2023.02.25.530017. bioRxiv. 2023. PMID: 36865313 Free PMC article. Updated. Preprint.
ZCCHC17 modulates neuronal RNA splicing and supports cognitive resilience in Alzheimer's disease.
Bartosch AMW, Youth EHH, Hansen S, Kaufman ME, Xiao H, Koo SY, Ashok A, Sivakumar S, Soni RK, Dumitrescu LC, Lam TG, Ropri AS, Lee AJ, Klein HU, Vardarajan BN, Bennett DA, Young-Pearse TL, De Jager PL, Hohman TJ, Sproul AA, Teich AF. Bartosch AMW, et al. Among authors: klein hu. bioRxiv [Preprint]. 2023 Mar 21:2023.03.21.533654. doi: 10.1101/2023.03.21.533654. bioRxiv. 2023. PMID: 36993746 Free PMC article. Updated. Preprint.
249 results