Klein DC - Search Results

1

De novo discovery of serotonin N-acetyltransferase inhibitors.

Szewczuk LM, Saldanha SA, Ganguly S, Bowers EM, Javoroncov M, Karanam B, Culhane JC, Holbert MA, Klein DC, Abagyan R, Cole PA. Szewczuk LM, et al. Among authors: klein dc. J Med Chem. 2007 Nov 1;50(22):5330-8. doi: 10.1021/jm0706463. Epub 2007 Oct 9. J Med Chem. 2007. PMID: 17924613 Free PMC article.

2

Cellular stability of serotonin N-acetyltransferase conferred by phosphonodifluoromethylene alanine (Pfa) substitution for Ser-205.

Zheng W, Schwarzer D, Lebeau A, Weller JL, Klein DC, Cole PA. Zheng W, et al. Among authors: klein dc. J Biol Chem. 2005 Mar 18;280(11):10462-7. doi: 10.1074/jbc.M412283200. Epub 2005 Jan 4. J Biol Chem. 2005. PMID: 15632116 Free article.

3

Enzymatic and cellular study of a serotonin N-acetyltransferase phosphopantetheine-based prodrug.

Hwang Y, Ganguly S, Ho AK, Klein DC, Cole PA. Hwang Y, et al. Among authors: klein dc. Bioorg Med Chem. 2007 Mar 1;15(5):2147-55. doi: 10.1016/j.bmc.2006.12.016. Epub 2006 Dec 13. Bioorg Med Chem. 2007. PMID: 17258461 Free PMC article.

4

Cellular stabilization of the melatonin rhythm enzyme induced by nonhydrolyzable phosphonate incorporation.

Zheng W, Zhang Z, Ganguly S, Weller JL, Klein DC, Cole PA. Zheng W, et al. Among authors: klein dc. Nat Struct Biol. 2003 Dec;10(12):1054-7. doi: 10.1038/nsb1005. Epub 2003 Oct 26. Nat Struct Biol. 2003. PMID: 14578935

5

Kinetic analysis of the catalytic mechanism of serotonin N-acetyltransferase (EC 2.3.1.87).

De Angelis J, Gastel J, Klein DC, Cole PA. De Angelis J, et al. Among authors: klein dc. J Biol Chem. 1998 Jan 30;273(5):3045-50. doi: 10.1074/jbc.273.5.3045. J Biol Chem. 1998. PMID: 9446620 Free article.

6

Evidence that proline focuses movement of the floppy loop of arylalkylamine N-acetyltransferase (EC 2.3.1.87).

Pavlicek J, Coon SL, Ganguly S, Weller JL, Hassan SA, Sackett DL, Klein DC. Pavlicek J, et al. Among authors: klein dc. J Biol Chem. 2008 May 23;283(21):14552-8. doi: 10.1074/jbc.M800593200. Epub 2008 Mar 24. J Biol Chem. 2008. PMID: 18362150 Free PMC article.

7

Control of melatonin synthesis in the mammalian pineal gland: the critical role of serotonin acetylation.

Ganguly S, Coon SL, Klein DC. Ganguly S, et al. Among authors: klein dc. Cell Tissue Res. 2002 Jul;309(1):127-37. doi: 10.1007/s00441-002-0579-y. Epub 2002 May 29. Cell Tissue Res. 2002. PMID: 12111543 Review.

8

Crystal structure of the 14-3-3zeta:serotonin N-acetyltransferase complex. a role for scaffolding in enzyme regulation.

Obsil T, Ghirlando R, Klein DC, Ganguly S, Dyda F. Obsil T, et al. Among authors: klein dc. Cell. 2001 Apr 20;105(2):257-67. doi: 10.1016/s0092-8674(01)00316-6. Cell. 2001. PMID: 11336675 Free article.

9

Melatonin synthesis: 14-3-3-dependent activation and inhibition of arylalkylamine N-acetyltransferase mediated by phosphoserine-205.

Ganguly S, Weller JL, Ho A, Chemineau P, Malpaux B, Klein DC. Ganguly S, et al. Among authors: klein dc. Proc Natl Acad Sci U S A. 2005 Jan 25;102(4):1222-7. doi: 10.1073/pnas.0406871102. Epub 2005 Jan 11. Proc Natl Acad Sci U S A. 2005. PMID: 15644438 Free PMC article.

10

Characterization of the Saccharomyces cerevisiae homolog of the melatonin rhythm enzyme arylalkylamine N-acetyltransferase (EC 2.3.1.87).

Ganguly S, Mummaneni P, Steinbach PJ, Klein DC, Coon SL. Ganguly S, et al. Among authors: klein dc. J Biol Chem. 2001 Dec 14;276(50):47239-47. doi: 10.1074/jbc.M107222200. Epub 2001 Sep 14. J Biol Chem. 2001. PMID: 11559708 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

345 results

Search Page