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Synergistic targeting and resistance to PARP inhibition in DNA damage repair-deficient pancreatic cancer.
Gout J, Perkhofer L, Morawe M, Arnold F, Ihle M, Biber S, Lange S, Roger E, Kraus JM, Stifter K, Hahn SA, Zamperone A, Engleitner T, Müller M, Walter K, Rodriguez-Aznar E, Sainz B Jr, Hermann PC, Hessmann E, Müller S, Azoitei N, Lechel A, Liebau S, Wagner M, Simeone DM, Kestler HA, Seufferlein T, Wiesmüller L, Rad R, Frappart PO, Kleger A. Gout J, et al. Among authors: kleger a. Gut. 2021 Apr;70(4):743-760. doi: 10.1136/gutjnl-2019-319970. Epub 2020 Sep 1. Gut. 2021. PMID: 32873698 Free PMC article.
Loss of ORP3 induces aneuploidy and promotes bladder cancer cell invasion through deregulated microtubule and actin dynamics.
Wang X, Liu J, Azoitei A, Eiseler T, Meessen S, Jiang W, Zheng X, Makori AW, Eckstein M, Hartmann A, Stilgenbauer S, Elati M, Hohwieler M, Kleger A, John A, Zengerling F, Wezel F, Bolenz C, Günes C. Wang X, et al. Among authors: kleger a. Cell Mol Life Sci. 2023 Sep 22;80(10):299. doi: 10.1007/s00018-023-04959-6. Cell Mol Life Sci. 2023. PMID: 37740130 Free PMC article.
Protein kinase D2 is an essential regulator of murine myoblast differentiation.
Kleger A, Loebnitz C, Pusapati GV, Armacki M, Müller M, Tümpel S, Illing A, Hartmann D, Brunner C, Liebau S, Rudolph KL, Adler G, Seufferlein T. Kleger A, et al. PLoS One. 2011 Jan 27;6(1):e14599. doi: 10.1371/journal.pone.0014599. PLoS One. 2011. PMID: 21298052 Free PMC article.
Protein kinase D2 is a novel regulator of glioblastoma growth and tumor formation.
Azoitei N, Kleger A, Schoo N, Thal DR, Brunner C, Pusapati GV, Filatova A, Genze F, Möller P, Acker T, Kuefer R, Van Lint J, Baust H, Adler G, Seufferlein T. Azoitei N, et al. Among authors: kleger a. Neuro Oncol. 2011 Jul;13(7):710-24. doi: 10.1093/neuonc/nor084. Neuro Oncol. 2011. PMID: 21727210 Free PMC article.
155 results