Kleemann R - Search Results

1

Intervention with isoleucine or valine corrects hyperinsulinemia and reduces intrahepatic diacylglycerols, liver steatosis, and inflammation in Ldlr-/-.Leiden mice with manifest obesity-associated NASH.

Gart E, van Duyvenvoorde W, Caspers MPM, van Trigt N, Snabel J, Menke A, Keijer J, Salic K, Morrison MC, Kleemann R. Gart E, et al. Among authors: kleemann r. FASEB J. 2022 Aug;36(8):e22435. doi: 10.1096/fj.202200111R. FASEB J. 2022. PMID: 35830259

2

The challenges for molecular nutrition research 2: quantification of the nutritional phenotype.

van Ommen B, Keijer J, Kleemann R, Elliott R, Drevon CA, McArdle H, Gibney M, Müller M. van Ommen B, et al. Among authors: kleemann r. Genes Nutr. 2008 Jul;3(2):51-9. doi: 10.1007/s12263-008-0084-3. Epub 2008 Jun 25. Genes Nutr. 2008. PMID: 18850187 Free PMC article.

3

Alterations in hepatic one-carbon metabolism and related pathways following a high-fat dietary intervention.

Rubio-Aliaga I, Roos Bd, Sailer M, McLoughlin GA, Boekschoten MV, van Erk M, Bachmair EM, van Schothorst EM, Keijer J, Coort SL, Evelo C, Gibney MJ, Daniel H, Muller M, Kleemann R, Brennan L. Rubio-Aliaga I, et al. Among authors: kleemann r. Physiol Genomics. 2011 Apr 27;43(8):408-16. doi: 10.1152/physiolgenomics.00179.2010. Epub 2011 Feb 8. Physiol Genomics. 2011. PMID: 21303933

4

A dietary mixture containing fish oil, resveratrol, lycopene, catechins, and vitamins E and C reduces atherosclerosis in transgenic mice.

Verschuren L, Wielinga PY, van Duyvenvoorde W, Tijani S, Toet K, van Ommen B, Kooistra T, Kleemann R. Verschuren L, et al. Among authors: kleemann r. J Nutr. 2011 May;141(5):863-9. doi: 10.3945/jn.110.133751. Epub 2011 Mar 16. J Nutr. 2011. PMID: 21411607 Free PMC article.

5

Anti-inflammatory, anti-proliferative and anti-atherosclerotic effects of quercetin in human in vitro and in vivo models.

Kleemann R, Verschuren L, Morrison M, Zadelaar S, van Erk MJ, Wielinga PY, Kooistra T. Kleemann R, et al. Atherosclerosis. 2011 Sep;218(1):44-52. doi: 10.1016/j.atherosclerosis.2011.04.023. Epub 2011 May 5. Atherosclerosis. 2011. PMID: 21601209

6

Differential effects of drug interventions and dietary lifestyle in developing type 2 diabetes and complications: a systems biology analysis in LDLr-/- mice.

Radonjic M, Wielinga PY, Wopereis S, Kelder T, Goelela VS, Verschuren L, Toet K, van Duyvenvoorde W, van der Werff van der Vat B, Stroeve JH, Cnubben N, Kooistra T, van Ommen B, Kleemann R. Radonjic M, et al. Among authors: kleemann r. PLoS One. 2013;8(2):e56122. doi: 10.1371/journal.pone.0056122. Epub 2013 Feb 15. PLoS One. 2013. PMID: 23457508 Free PMC article.

7

Effects of chocolate supplementation on metabolic and cardiovascular parameters in ApoE3L mice fed a high-cholesterol atherogenic diet.

Yakala GK, Wielinga PY, Suarez M, Bunschoten A, van Golde JM, Arola L, Keijer J, Kleemann R, Kooistra T, Heeringa P. Yakala GK, et al. Among authors: kleemann r. Mol Nutr Food Res. 2013 Nov;57(11):2039-48. doi: 10.1002/mnfr.201200858. Epub 2013 Aug 15. Mol Nutr Food Res. 2013. PMID: 23946229

8

Combined analysis of pharmacokinetic and efficacy data of preclinical studies with statins markedly improves translation of drug efficacy to human trials.

van de Steeg E, Kleemann R, Jansen HT, van Duyvenvoorde W, Offerman EH, Wortelboer HM, Degroot J. van de Steeg E, et al. Among authors: kleemann r. J Pharmacol Exp Ther. 2013 Dec;347(3):635-44. doi: 10.1124/jpet.113.208595. Epub 2013 Sep 18. J Pharmacol Exp Ther. 2013. PMID: 24049060

9

Epicatechin attenuates atherosclerosis and exerts anti-inflammatory effects on diet-induced human-CRP and NFκB in vivo.

Morrison M, van der Heijden R, Heeringa P, Kaijzel E, Verschuren L, Blomhoff R, Kooistra T, Kleemann R. Morrison M, et al. Among authors: kleemann r. Atherosclerosis. 2014 Mar;233(1):149-56. doi: 10.1016/j.atherosclerosis.2013.12.027. Epub 2014 Jan 8. Atherosclerosis. 2014. PMID: 24529136

10

Metabolically induced liver inflammation leads to NASH and differs from LPS- or IL-1β-induced chronic inflammation.

Liang W, Lindeman JH, Menke AL, Koonen DP, Morrison M, Havekes LM, van den Hoek AM, Kleemann R. Liang W, et al. Among authors: kleemann r. Lab Invest. 2014 May;94(5):491-502. doi: 10.1038/labinvest.2014.11. Epub 2014 Feb 24. Lab Invest. 2014. PMID: 24566933 Free article.

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