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A strategy for systemic toxicity assessment based on non-animal approaches: The Cosmetics Europe Long Range Science Strategy programme.
Desprez B, Dent M, Keller D, Klaric M, Ouédraogo G, Cubberley R, Duplan H, Eilstein J, Ellison C, Grégoire S, Hewitt NJ, Jacques-Jamin C, Lange D, Roe A, Rothe H, Blaauboer BJ, Schepky A, Mahony C. Desprez B, et al. Among authors: klaric m. Toxicol In Vitro. 2018 Aug;50:137-146. doi: 10.1016/j.tiv.2018.02.017. Epub 2018 Mar 2. Toxicol In Vitro. 2018. PMID: 29499337 Review.
Challenges in working towards an internal threshold of toxicological concern (iTTC) for use in the safety assessment of cosmetics: Discussions from the Cosmetics Europe iTTC Working Group workshop.
Ellison CA, Blackburn KL, Carmichael PL, Clewell HJ 3rd, Cronin MTD, Desprez B, Escher SE, Ferguson SS, Grégoire S, Hewitt NJ, Hollnagel HM, Klaric M, Patel A, Salhi S, Schepky A, Schmitt BG, Wambaugh JF, Worth A. Ellison CA, et al. Among authors: klaric m. Regul Toxicol Pharmacol. 2019 Apr;103:63-72. doi: 10.1016/j.yrtph.2019.01.016. Epub 2019 Jan 15. Regul Toxicol Pharmacol. 2019. PMID: 30653989 Free PMC article. Review.
A mode-of-action ontology model for safety evaluation of chemicals: Outcome of a series of workshops on repeated dose toxicity.
Desprez B, Birk B, Blaauboer B, Boobis A, Carmichael P, Cronin MTD, Curie R, Daston G, Hubesch B, Jennings P, Klaric M, Kroese D, Mahony C, Ouédraogo G, Piersma A, Richarz AN, Schwarz M, van Benthem J, van de Water B, Vinken M. Desprez B, et al. Among authors: klaric m. Toxicol In Vitro. 2019 Sep;59:44-50. doi: 10.1016/j.tiv.2019.04.005. Epub 2019 Apr 4. Toxicol In Vitro. 2019. PMID: 30954655
Use of human liver and EpiSkin™ S9 subcellular fractions as a screening assays to compare the in vitro hepatic and dermal metabolism of 47 cosmetics-relevant chemicals.
Eilstein J, Grégoire S, Fabre A, Arbey E, Géniès C, Duplan H, Rothe H, Ellison C, Cubberley R, Schepky A, Lange D, Klaric M, Hewitt NJ, Jacques-Jamin C. Eilstein J, et al. Among authors: klaric m. J Appl Toxicol. 2020 Mar;40(3):416-433. doi: 10.1002/jat.3914. Epub 2020 Jan 8. J Appl Toxicol. 2020. PMID: 31912921
Partition coefficient and diffusion coefficient determinations of 50 compounds in human intact skin, isolated skin layers and isolated stratum corneum lipids.
Ellison CA, Tankersley KO, Obringer CM, Carr GJ, Manwaring J, Rothe H, Duplan H, Géniès C, Grégoire S, Hewitt NJ, Jamin CJ, Klaric M, Lange D, Rolaki A, Schepky A. Ellison CA, et al. Among authors: klaric m. Toxicol In Vitro. 2020 Dec;69:104990. doi: 10.1016/j.tiv.2020.104990. Epub 2020 Sep 1. Toxicol In Vitro. 2020. PMID: 32882340 Free article.
Read-across and new approach methodologies applied in a 10-step framework for cosmetics safety assessment - A case study with parabens.
Ouedraogo G, Alexander-White C, Bury D, Clewell HJ 3rd, Cronin M, Cull T, Dent M, Desprez B, Detroyer A, Ellison C, Giammanco S, Hack E, Hewitt NJ, Kenna G, Klaric M, Kreiling R, Lester C, Mahony C, Mombelli E, Naciff J, O'Brien J, Schepky A, Tozer S, van der Burg B, van Vugt-Lussenburg B, Stuard S, Cosmetics Europe. Ouedraogo G, et al. Among authors: klaric m. Regul Toxicol Pharmacol. 2022 Jul;132:105161. doi: 10.1016/j.yrtph.2022.105161. Epub 2022 May 1. Regul Toxicol Pharmacol. 2022. PMID: 35508214 Free article.
Comparison of the metabolism of 10 chemicals in human and pig skin explants.
Géniès C, Jamin EL, Debrauwer L, Zalko D, Person EN, Eilstein J, Grégoire S, Schepky A, Lange D, Ellison C, Roe A, Salhi S, Cubberley R, Hewitt NJ, Rothe H, Klaric M, Duplan H, Jacques-Jamin C. Géniès C, et al. Among authors: klaric m. J Appl Toxicol. 2019 Feb;39(2):385-397. doi: 10.1002/jat.3730. Epub 2018 Oct 21. J Appl Toxicol. 2019. PMID: 30345528 Free PMC article.
Systematic evaluation of non-animal test methods for skin sensitisation safety assessment.
Reisinger K, Hoffmann S, Alépée N, Ashikaga T, Barroso J, Elcombe C, Gellatly N, Galbiati V, Gibbs S, Groux H, Hibatallah J, Keller D, Kern P, Klaric M, Kolle S, Kuehnl J, Lambrechts N, Lindstedt M, Millet M, Martinozzi-Teissier S, Natsch A, Petersohn D, Pike I, Sakaguchi H, Schepky A, Tailhardat M, Templier M, van Vliet E, Maxwell G. Reisinger K, et al. Among authors: klaric m. Toxicol In Vitro. 2015 Feb;29(1):259-70. doi: 10.1016/j.tiv.2014.10.018. Toxicol In Vitro. 2015. PMID: 25448812 Free article.
109 results