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A small-molecule fusion inhibitor of influenza virus is orally active in mice.
van Dongen MJP, Kadam RU, Juraszek J, Lawson E, Brandenburg B, Schmitz F, Schepens WBG, Stoops B, van Diepen HA, Jongeneelen M, Tang C, Vermond J, van Eijgen-Obregoso Real A, Blokland S, Garg D, Yu W, Goutier W, Lanckacker E, Klap JM, Peeters DCG, Wu J, Buyck C, Jonckers THM, Roymans D, Roevens P, Vogels R, Koudstaal W, Friesen RHE, Raboisson P, Dhanak D, Goudsmit J, Wilson IA. van Dongen MJP, et al. Among authors: klap jm. Science. 2019 Mar 8;363(6431):eaar6221. doi: 10.1126/science.aar6221. Science. 2019. PMID: 30846569 Free PMC article.
A pan-influenza monoclonal antibody neutralizes H5 strains and prophylactically protects through intranasal administration.
Beukenhorst AL, Frallicciardi J, Rice KL, Koldijk MH, Moreira de Mello JC, Klap JM, Hadjichrysanthou C, Koch CM, da Costa KAS, Temperton N, de Jong BA, Vietsch H, Ziere B, Julg B, Koudstaal W, Goudsmit J. Beukenhorst AL, et al. Among authors: klap jm. Sci Rep. 2024 Feb 15;14(1):3818. doi: 10.1038/s41598-024-53049-5. Sci Rep. 2024. PMID: 38360813 Free PMC article.
Multi-Omics Analysis Reveals MicroRNAs Associated With Cardiometabolic Traits.
Mens MMJ, Maas SCE, Klap J, Weverling GJ, Klatser P, Brakenhoff JPJ, van Meurs JBJ, Uitterlinden AG, Ikram MA, Kavousi M, Ghanbari M. Mens MMJ, et al. Front Genet. 2020 Feb 27;11:110. doi: 10.3389/fgene.2020.00110. eCollection 2020. Front Genet. 2020. PMID: 32174972 Free PMC article.
13 results