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Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S.
Chem Sci. 2019 Oct 4;10(46):10789-10801. doi: 10.1039/c9sc03445e. eCollection 2019 Dec 14.
Chem Sci. 2019.
PMID: 31857889
Free PMC article.
Targeting Her2-insYVMA with Covalent Inhibitors-A Focused Compound Screening and Structure-Based Design Approach.
Lategahn J, Hardick J, Grabe T, Niggenaber J, Jeyakumar K, Keul M, Tumbrink HL, Becker C, Hodson L, Kirschner T, Klövekorn P, Ketzer J, Baumann M, Terheyden S, Unger A, Weisner J, Müller MP, van Otterlo WAL, Bauer S, Rauh D.
Lategahn J, et al. Among authors: klovekorn p.
J Med Chem. 2020 Oct 22;63(20):11725-11755. doi: 10.1021/acs.jmedchem.0c00870. Epub 2020 Sep 30.
J Med Chem. 2020.
PMID: 32931277
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Design and synthesis of 1H-pyrazolo[3,4-b]pyridines targeting mitogen-activated protein kinase kinase 4 (MKK4) - A promising target for liver regeneration.
Pfaffenrot B, Klövekorn P, Juchum M, Selig R, Albrecht W, Zender L, Laufer SA.
Pfaffenrot B, et al. Among authors: klovekorn p.
Eur J Med Chem. 2021 Jun 5;218:113371. doi: 10.1016/j.ejmech.2021.113371. Epub 2021 Mar 17.
Eur J Med Chem. 2021.
PMID: 33794385
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From off-to on-target: New BRAF-inhibitor-template-derived compounds selectively targeting mitogen activated protein kinase kinase 4 (MKK4).
Klövekorn P, Pfaffenrot B, Juchum M, Selig R, Albrecht W, Zender L, Laufer SA.
Klövekorn P, et al.
Eur J Med Chem. 2021 Jan 15;210:112963. doi: 10.1016/j.ejmech.2020.112963. Epub 2020 Oct 24.
Eur J Med Chem. 2021.
PMID: 33199152
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Scaffold modified Vemurafenib analogues as highly selective mitogen activated protein kinase kinase 4 (MKK4) inhibitors.
Juchum M, Pfaffenrot B, Klövekorn P, Selig R, Albrecht W, Zender L, Laufer SA.
Juchum M, et al. Among authors: klovekorn p.
Eur J Med Chem. 2022 Oct 5;240:114584. doi: 10.1016/j.ejmech.2022.114584. Epub 2022 Jul 8.
Eur J Med Chem. 2022.
PMID: 35868124
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Variable optical delay line with diffraction-limited autoalignment.
Klövekorn P, Munch J.
Klövekorn P, et al.
Appl Opt. 1998 Apr 1;37(10):1903-4. doi: 10.1364/ao.37.001903.
Appl Opt. 1998.
PMID: 18273107
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Variable stimulated Brillouin scattering pulse compressor for nonlinear optical measurements.
Klövekorn P, Munch J.
Klövekorn P, et al.
Appl Opt. 1997 Aug 20;36(24):5913-7. doi: 10.1364/ao.36.005913.
Appl Opt. 1997.
PMID: 18259429
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Intrinsic plasma volume deficits in patients with coronary artery disease. Effects of myocardial revascularization.
Cohn LH, Klovekorn P, Moore FD, Collins JJ Jr.
Cohn LH, et al. Among authors: klovekorn p.
Arch Surg. 1974 Jan;108(1):57-60. doi: 10.1001/archsurg.1974.01350250049013.
Arch Surg. 1974.
PMID: 4543371
No abstract available.
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