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Page 1
Global hypomethylation in childhood asthma identified by genome-wide DNA-methylation sequencing preferentially affects enhancer regions.
Thürmann L, Klös M, Mackowiak SD, Bieg M, Bauer T, Ishaque N, Messingschlager M, Herrmann C, Röder S, Bauer M, Schäuble S, Faessler E, Hahn U, Weichenhan D, Mücke O, Plass C, Borte M, von Mutius E, Stangl GI, Lauener R, Karvonen AM, Divaret-Chauveau A, Riedler J, Heinrich J, Standl M, von Berg A, Schaaf B, Herberth G, Kabesch M, Eils R, Trump S, Lehmann I. Thürmann L, et al. Among authors: klos m. Allergy. 2023 Jun;78(6):1489-1506. doi: 10.1111/all.15658. Epub 2023 Feb 10. Allergy. 2023. PMID: 36704932
Early-onset childhood atopic dermatitis is related to NLRP2 repression.
Thürmann L, Grützmann K, Klös M, Bieg M, Winter M, Polte T, Bauer T, Schick M, Bewerunge-Hudler M, Röder S, Bauer M, Wissenbach DK, Sack U, Weichenhan D, Mücke O, Plass C, Borte M, von Bergen M, Lehmann I, Eils R, Trump S. Thürmann L, et al. Among authors: klos m. J Allergy Clin Immunol. 2018 Apr;141(4):1482-1485.e16. doi: 10.1016/j.jaci.2017.11.018. Epub 2017 Dec 9. J Allergy Clin Immunol. 2018. PMID: 29233739 Free article. No abstract available.
Longitudinal trends of serum IgE and IL5RA expression throughout childhood are associated with asthma but not with persistent wheeze.
Klös M, Thürmann L, Bauer M, Heinrich J, Standl M, von Berg A, Schaaf B, Weichenhan D, Mücke O, Plass C, Röder S, Herberth G, Sack U, Borte M, Stangl GI, Eils R, Trump S, Lehmann I. Klös M, et al. Allergy. 2019 Oct;74(10):2002-2006. doi: 10.1111/all.13837. Epub 2019 May 21. Allergy. 2019. PMID: 31012487 No abstract available.
Genome-wide DNA methylation sequencing identifies epigenetic perturbations in the upper airways under long-term exposure to moderate levels of ambient air pollution.
Messingschlager M, Bartel-Steinbach M, Mackowiak SD, Denkena J, Bieg M, Klös M, Seegebarth A, Straff W, Süring K, Ishaque N, Eils R, Lehmann I, Lermen D, Trump S. Messingschlager M, et al. Among authors: klos m. Environ Res. 2023 Sep 15;233:116413. doi: 10.1016/j.envres.2023.116413. Epub 2023 Jun 20. Environ Res. 2023. PMID: 37343754 Free article.
Genome-wide DNA promoter methylation and transcriptome analysis in human adipose tissue unravels novel candidate genes for obesity.
Keller M, Hopp L, Liu X, Wohland T, Rohde K, Cancello R, Klös M, Bacos K, Kern M, Eichelmann F, Dietrich A, Schön MR, Gärtner D, Lohmann T, Dreßler M, Stumvoll M, Kovacs P, DiBlasio AM, Ling C, Binder H, Blüher M, Böttcher Y. Keller M, et al. Among authors: klos m. Mol Metab. 2016 Nov 16;6(1):86-100. doi: 10.1016/j.molmet.2016.11.003. eCollection 2017 Jan. Mol Metab. 2016. PMID: 28123940 Free PMC article.
DNA methylation of SSPN is linked to adipose tissue distribution and glucose metabolism.
Keller M, Klös M, Rohde K, Krüger J, Kurze T, Dietrich A, Schön MR, Gärtner D, Lohmann T, Dreßler M, Stumvoll M, Blüher M, Kovacs P, Böttcher Y. Keller M, et al. Among authors: klos m. FASEB J. 2018 Jun 22:fj201800528R. doi: 10.1096/fj.201800528R. Online ahead of print. FASEB J. 2018. PMID: 29932866
Our data strongly support the role of the SSPN locus in body fat composition and glucose homeostasis, and suggest that this is most likely the result of changes in DNA methylation of SSPN in adipose tissue.-Keller, M., Klos, M., Rohde, K., Kruger, J., Kurze, …
Our data strongly support the role of the SSPN locus in body fat composition and glucose homeostasis, and suggest that this is most likely t …
Adipose tissue depot specific promoter methylation of TMEM18.
Rohde K, Keller M, Klös M, Schleinitz D, Dietrich A, Schön MR, Gärtner D, Lohmann T, Dreßler M, Stumvoll M, Kovacs P, Blüher M, Böttcher Y. Rohde K, et al. Among authors: klos m. J Mol Med (Berl). 2014 Aug;92(8):881-8. doi: 10.1007/s00109-014-1154-1. Epub 2014 Apr 26. J Mol Med (Berl). 2014. PMID: 24763707
Engineered nanoparticles promote cardiac tropism of AAV vectors.
Switala L, Di L, Gao H, Asase C, Klos M, Rengasamy P, Fedyukina D, Maiseyeu A. Switala L, et al. Among authors: klos m. J Nanobiotechnology. 2024 May 3;22(1):223. doi: 10.1186/s12951-024-02485-6. J Nanobiotechnology. 2024. PMID: 38702815 Free PMC article.
Effect of the Factor XIa Inhibitor Asundexian According to Baseline Infarct Pattern and on MRI Covert Infarct Outcomes.
Smith EE, Shoamanesh A, Xu L, Heenan L, Saad F, Colorado P, Chen CH, Lemmens R, De Marchis GM, Caso V, Masjuan J, Hirano T, Milanov I, Campbell BCV, Mas JL, Connolly SJ, Mundl H, Hart RG; PACIFIC-Stroke Steering Committee and Investigators. Smith EE, et al. Stroke. 2024 Feb;55(2):392-402. doi: 10.1161/STROKEAHA.123.043198. Epub 2024 Jan 4. Stroke. 2024. PMID: 38174569 Clinical Trial.
138 results