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Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity.
Hoffmann M, Hofmann-Winkler H, Smith JC, Krüger N, Sørensen LK, Søgaard OS, Hasselstrøm JB, Winkler M, Hempel T, Raich L, Olsson S, Yamazoe T, Yamatsuta K, Mizuno H, Ludwig S, Noé F, Sheltzer JM, Kjolby M, Pöhlmann S. Hoffmann M, et al. Among authors: kjolby m. bioRxiv [Preprint]. 2020 Aug 5:2020.08.05.237651. doi: 10.1101/2020.08.05.237651. bioRxiv. 2020. PMID: 32793911 Free PMC article. Updated. Preprint.
Camostat mesylate against SARS-CoV-2 and COVID-19-Rationale, dosing and safety.
Breining P, Frølund AL, Højen JF, Gunst JD, Staerke NB, Saedder E, Cases-Thomas M, Little P, Nielsen LP, Søgaard OS, Kjolby M. Breining P, et al. Among authors: kjolby m. Basic Clin Pharmacol Toxicol. 2021 Feb;128(2):204-212. doi: 10.1111/bcpt.13533. Epub 2020 Nov 22. Basic Clin Pharmacol Toxicol. 2021. PMID: 33176395 Free article. Review.
Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity.
Hoffmann M, Hofmann-Winkler H, Smith JC, Krüger N, Arora P, Sørensen LK, Søgaard OS, Hasselstrøm JB, Winkler M, Hempel T, Raich L, Olsson S, Danov O, Jonigk D, Yamazoe T, Yamatsuta K, Mizuno H, Ludwig S, Noé F, Kjolby M, Braun A, Sheltzer JM, Pöhlmann S. Hoffmann M, et al. Among authors: kjolby m. EBioMedicine. 2021 Mar;65:103255. doi: 10.1016/j.ebiom.2021.103255. Epub 2021 Mar 4. EBioMedicine. 2021. PMID: 33676899 Free PMC article.
Efficacy of the TMPRSS2 inhibitor camostat mesilate in patients hospitalized with Covid-19-a double-blind randomized controlled trial.
Gunst JD, Staerke NB, Pahus MH, Kristensen LH, Bodilsen J, Lohse N, Dalgaard LS, Brønnum D, Fröbert O, Hønge B, Johansen IS, Monrad I, Erikstrup C, Rosendal R, Vilstrup E, Mariager T, Bove DG, Offersen R, Shakar S, Cajander S, Jørgensen NP, Sritharan SS, Breining P, Jespersen S, Mortensen KL, Jensen ML, Kolte L, Frattari GS, Larsen CS, Storgaard M, Nielsen LP, Tolstrup M, Sædder EA, Østergaard LJ, Ngo HTT, Jensen MH, Højen JF, Kjolby M, Søgaard OS. Gunst JD, et al. Among authors: kjolby m. EClinicalMedicine. 2021 May;35:100849. doi: 10.1016/j.eclinm.2021.100849. Epub 2021 Apr 22. EClinicalMedicine. 2021. PMID: 33903855 Free PMC article.
The Impact of IFNλ4 on the Adaptive Immune Response to SARS-CoV-2 Infection.
Møhlenberg M, Monrad I, Vibholm LK, Nielsen SSF, Frattari GS, Schleimann MH, Olesen R, Kjolby M, Gunst JD, Søgaard OS, O'Brien TR, Tolstrup M, Hartmann R. Møhlenberg M, et al. Among authors: kjolby m. J Interferon Cytokine Res. 2021 Nov;41(11):407-414. doi: 10.1089/jir.2021.0106. J Interferon Cytokine Res. 2021. PMID: 34788130 Free PMC article.
TLR2 and TLR7 mediate distinct immunopathological and antiviral plasmacytoid dendritic cell responses to SARS-CoV-2 infection.
van der Sluis RM, Cham LB, Gris-Oliver A, Gammelgaard KR, Pedersen JG, Idorn M, Ahmadov U, Hernandez SS, Cémalovic E, Godsk SH, Thyrsted J, Gunst JD, Nielsen SD, Jørgensen JJ, Bjerg TW, Laustsen A, Reinert LS, Olagnier D, Bak RO, Kjolby M, Holm CK, Tolstrup M, Paludan SR, Kristensen LS, Søgaard OS, Jakobsen MR. van der Sluis RM, et al. Among authors: kjolby m. EMBO J. 2022 May 16;41(10):e109622. doi: 10.15252/embj.2021109622. Epub 2022 Mar 1. EMBO J. 2022. PMID: 35178710 Free PMC article.
Sortilin as a Biomarker for Cardiovascular Disease Revisited.
Møller PL, Rohde PD, Winther S, Breining P, Nissen L, Nykjaer A, Bøttcher M, Nyegaard M, Kjolby M. Møller PL, et al. Among authors: kjolby m. Front Cardiovasc Med. 2021 Apr 16;8:652584. doi: 10.3389/fcvm.2021.652584. eCollection 2021. Front Cardiovasc Med. 2021. PMID: 33937362 Free PMC article.
Multi-Trait Genomic Risk Stratification for Type 2 Diabetes.
Rohde PD, Nyegaard M, Kjolby M, Sørensen P. Rohde PD, et al. Among authors: kjolby m. Front Med (Lausanne). 2021 Sep 8;8:711208. doi: 10.3389/fmed.2021.711208. eCollection 2021. Front Med (Lausanne). 2021. PMID: 34568370 Free PMC article.
58 results