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C-Type Lectin Receptor DCAR Recognizes Mycobacterial Phosphatidyl-Inositol Mannosides to Promote a Th1 Response during Infection.
Toyonaga K, Torigoe S, Motomura Y, Kamichi T, Hayashi JM, Morita YS, Noguchi N, Chuma Y, Kiyohara H, Matsuo K, Tanaka H, Nakagawa Y, Sakuma T, Ohmuraya M, Yamamoto T, Umemura M, Matsuzaki G, Yoshikai Y, Yano I, Miyamoto T, Yamasaki S. Toyonaga K, et al. Among authors: kiyohara h. Immunity. 2016 Dec 20;45(6):1245-1257. doi: 10.1016/j.immuni.2016.10.012. Epub 2016 Nov 22. Immunity. 2016. PMID: 27887882 Free article.
The liposome of trehalose dimycolate extracted from M. bovis BCG induces antitumor immunity via the activation of dendritic cells and CD8+ T cells.
Shiga M, Miyazaki J, Tanuma K, Nagumo Y, Yoshino T, Kandori S, Negoro H, Kojima T, Tanaka R, Okiyama N, Fujisawa Y, Watanabe M, Yamasaki S, Kiyohara H, Watanabe M, Sato TA, Tahara H, Nishiyama H, Yano I. Shiga M, et al. Among authors: kiyohara h. Cancer Immunol Immunother. 2021 Sep;70(9):2529-2543. doi: 10.1007/s00262-021-02870-2. Epub 2021 Feb 11. Cancer Immunol Immunother. 2021. PMID: 33570675 Free PMC article.
Cationized liposomal keto-mycolic acids isolated from Mycobacterium bovis bacillus Calmette-Guérin induce antitumor immunity in a syngeneic murine bladder cancer model.
Yoshino T, Miyazaki J, Kojima T, Kandori S, Shiga M, Kawahara T, Kimura T, Naka T, Kiyohara H, Watanabe M, Yamasaki S, Akaza H, Yano I, Nishiyama H. Yoshino T, et al. Among authors: kiyohara h. PLoS One. 2019 Jan 4;14(1):e0209196. doi: 10.1371/journal.pone.0209196. eCollection 2019. PLoS One. 2019. PMID: 30608942 Free PMC article.
Adjuvant activity of Mycobacteria-derived mycolic acids.
Kubota M, Iizasa E, Chuuma Y, Kiyohara H, Hara H, Yoshida H. Kubota M, et al. Among authors: kiyohara h. Heliyon. 2020 May 27;6(5):e04064. doi: 10.1016/j.heliyon.2020.e04064. eCollection 2020 May. Heliyon. 2020. PMID: 32490252 Free PMC article.
Efficacy of Dose Escalation of Oral 5-Aminosalicylic Acid for Ulcerative Colitis With a Mayo Endoscopic Subscore of 1: An Open Label Randomized Controlled Trial.
Fukuda T, Aoki Y, Kiyohara H, Yokoyama A, Nakazawa A, Yoshimatsu Y, Sugimoto S, Nanki K, Mikami Y, Fukuhara K, Mizuno S, Sujino T, Mutaguchi M, Takabayashi K, Morohoshi Y, Hosoda Y, Ogata H, Iwao Y, Naganuma M, Kanai T. Fukuda T, et al. Among authors: kiyohara h. Inflamm Bowel Dis. 2024 Apr 24:izae088. doi: 10.1093/ibd/izae088. Online ahead of print. Inflamm Bowel Dis. 2024. PMID: 38655866
Recent steroid use and the relapse risk in ulcerative colitis patients with endoscopic healing.
Fukuda T, Yamazaki H, Miyatani Y, Sawada T, Shibuya N, Fukuo Y, Kiyohara H, Morikubo H, Tominaga K, Kakimoto K, Imai T, Yaguchi K, Yamamoto S, Ando K, Nishimata N, Yoshihara T, Andoh A, Hibi T, Matsuoka K; IBD Terakoya Group. Fukuda T, et al. Among authors: kiyohara h. Aliment Pharmacol Ther. 2024 Apr 23. doi: 10.1111/apt.18013. Online ahead of print. Aliment Pharmacol Ther. 2024. PMID: 38651779
Real-world NUDT15 genotyping and thiopurine treatment optimization in inflammatory bowel disease: a multicenter study.
Makuuchi M, Kakuta Y, Umeno J, Fujii T, Takagawa T, Ibuka T, Miura M, Sasaki Y, Takahashi S, Nakase H, Kiyohara H, Tominaga K, Shimodaira Y, Hiraoka S, Ueno N, Yanai S, Yoshihara T, Kakimoto K, Matsuoka K, Hayashi R, Nanjo S, Iwama I, Ishiguro Y, Chiba H, Endo K, Kagaya T, Fukuda T, Sakata Y, Kudo T, Takagi T, Takahashi K, Naganuma M, Shinozaki M, Ogata N, Tanaka H, Narimatsu K, Miyazaki H, Ishige T, Onodera M, Hashimoto Y, Nagai H, Shimoyama Y, Naito T, Moroi R, Shiga H; Post-MENDEL study group; Kinouchi Y, Andoh A, Hisamatsu T, Masamune A. Makuuchi M, et al. Among authors: kiyohara h. J Gastroenterol. 2024 Apr 8. doi: 10.1007/s00535-024-02099-7. Online ahead of print. J Gastroenterol. 2024. PMID: 38589597
361 results