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Dasatinib and navitoclax act synergistically to target NUP98-NSD1+/FLT3-ITD+ acute myeloid leukemia.
Leukemia. 2019 Jun;33(6):1360-1372. doi: 10.1038/s41375-018-0327-2. Epub 2018 Dec 19.
Leukemia. 2019.
PMID: 30568173
FLT3-ITD allelic ratio and HLF expression predict FLT3 inhibitor efficacy in adult AML.
Kivioja J, Malani D, Kumar A, Kontro M, Parsons A, Kallioniemi O, Heckman CA.
Kivioja J, et al.
Sci Rep. 2021 Dec 7;11(1):23565. doi: 10.1038/s41598-021-03010-7.
Sci Rep. 2021.
PMID: 34876631
Free PMC article.
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Chimeric NUP98-NSD1 transcripts from the cryptic t(5;11)(q35.2;p15.4) in adult de novo acute myeloid leukemia.
Kivioja JL, Lopez Martí JM, Kumar A, Kontro M, Edgren H, Parsons A, Lundán T, Wolf M, Porkka K, Heckman CA.
Kivioja JL, et al.
Leuk Lymphoma. 2018 Mar;59(3):725-732. doi: 10.1080/10428194.2017.1357174. Epub 2017 Aug 4.
Leuk Lymphoma. 2018.
PMID: 28776436
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Inferring tumor-specific cancer dependencies through integrating ex vivo drug response assays and drug-protein profiling.
Batzilla A, Lu J, Kivioja J, Putzker K, Lewis J, Zenz T, Huber W.
Batzilla A, et al.
PLoS Comput Biol. 2022 Aug 22;18(8):e1010438. doi: 10.1371/journal.pcbi.1010438. eCollection 2022 Aug.
PLoS Comput Biol. 2022.
PMID: 35994503
Free PMC article.
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