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Metabolomic profiles predict individual multidisease outcomes.
Buergel T, Steinfeldt J, Ruyoga G, Pietzner M, Bizzarri D, Vojinovic D, Upmeier Zu Belzen J, Loock L, Kittner P, Christmann L, Hollmann N, Strangalies H, Braunger JM, Wild B, Chiesa ST, Spranger J, Klostermann F, van den Akker EB, Trompet S, Mooijaart SP, Sattar N, Jukema JW, Lavrijssen B, Kavousi M, Ghanbari M, Ikram MA, Slagboom E, Kivimaki M, Langenberg C, Deanfield J, Eils R, Landmesser U. Buergel T, et al. Among authors: kittner p. Nat Med. 2022 Nov;28(11):2309-2320. doi: 10.1038/s41591-022-01980-3. Epub 2022 Sep 22. Nat Med. 2022. PMID: 36138150 Free PMC article.
Neural network-based integration of polygenic and clinical information: development and validation of a prediction model for 10-year risk of major adverse cardiac events in the UK Biobank cohort.
Steinfeldt J, Buergel T, Loock L, Kittner P, Ruyoga G, Zu Belzen JU, Sasse S, Strangalies H, Christmann L, Hollmann N, Wolf B, Ference B, Deanfield J, Landmesser U, Eils R. Steinfeldt J, et al. Among authors: kittner p. Lancet Digit Health. 2022 Feb;4(2):e84-e94. doi: 10.1016/S2589-7500(21)00249-1. Lancet Digit Health. 2022. PMID: 35090679 Free article.
Brief Report: A Blood-Based MicroRNA Complementary Diagnostic Predicts Immunotherapy Efficacy in Advanced-Sta ge NSCLC With High Programmed Death-Ligand 1 Express ion.
Rajakumar T, Horos R, Kittner P, Kahraman M, Sikosek T, Hinkfoth F, Tikk K, Mercaldo ND, Stenzinger A, Rabe KF, Reck M, Thomas M, Christopoulos P, Steinkraus BR. Rajakumar T, et al. Among authors: kittner p. JTO Clin Res Rep. 2022 Jun 20;3(8):100369. doi: 10.1016/j.jtocrr.2022.100369. eCollection 2022 Aug. JTO Clin Res Rep. 2022. PMID: 35880086 Free PMC article.
A blood-based miRNA signature with prognostic value for overall survival in advanced stage non-small cell lung cancer treated with immunotherapy.
Rajakumar T, Horos R, Jehn J, Schenz J, Muley T, Pelea O, Hofmann S, Kittner P, Kahraman M, Heuvelman M, Sikosek T, Feufel J, Skottke J, Nötzel D, Hinkfoth F, Tikk K, Daniel-Moreno A, Ceiler J, Mercaldo N, Uhle F, Uhle S, Weigand MA, Elshiaty M, Lusky F, Schindler H, Ferry Q, Sauka-Spengler T, Wu Q, Rabe KF, Reck M, Thomas M, Christopoulos P, Steinkraus BR. Rajakumar T, et al. Among authors: kittner p. NPJ Precis Oncol. 2022 Mar 31;6(1):19. doi: 10.1038/s41698-022-00262-y. NPJ Precis Oncol. 2022. PMID: 35361874 Free PMC article.