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O-GalNAc glycosylation determines intracellular trafficking of APP and Aβ production.
Tachida Y, Iijima J, Takahashi K, Suzuki H, Kizuka Y, Yamaguchi Y, Tanaka K, Nakano M, Takakura D, Kawasaki N, Saito Y, Manya H, Endo T, Kitazume S. Tachida Y, et al. Among authors: kitazume s. J Biol Chem. 2023 Jul;299(7):104905. doi: 10.1016/j.jbc.2023.104905. Epub 2023 Jun 9. J Biol Chem. 2023. PMID: 37302553 Free PMC article.
α1,6-Fucosyltransferase (Fut8) is implicated in vulnerability to elastase-induced emphysema in mice and a possible non-invasive predictive marker for disease progression and exacerbations in chronic obstructive pulmonary disease (COPD).
Kamio K, Yoshida T, Gao C, Ishii T, Ota F, Motegi T, Kobayashi S, Fujinawa R, Ohtsubo K, Kitazume S, Angata T, Azuma A, Gemma A, Nishimura M, Betsuyaku T, Kida K, Taniguchi N. Kamio K, et al. Among authors: kitazume s. Biochem Biophys Res Commun. 2012 Jul 20;424(1):112-7. doi: 10.1016/j.bbrc.2012.06.081. Epub 2012 Jun 23. Biochem Biophys Res Commun. 2012. PMID: 22732410
In vivo cleavage of alpha2,6-sialyltransferase by Alzheimer beta-secretase.
Kitazume S, Nakagawa K, Oka R, Tachida Y, Ogawa K, Luo Y, Citron M, Shitara H, Taya C, Yonekawa H, Paulson JC, Miyoshi E, Taniguchi N, Hashimoto Y. Kitazume S, et al. J Biol Chem. 2005 Mar 4;280(9):8589-95. doi: 10.1074/jbc.M409417200. Epub 2004 Sep 13. J Biol Chem. 2005. PMID: 15364953 Free article.
Sialylation enhances the secretion of neurotoxic amyloid-beta peptides.
Nakagawa K, Kitazume S, Oka R, Maruyama K, Saido TC, Sato Y, Endo T, Hashimoto Y. Nakagawa K, et al. Among authors: kitazume s. J Neurochem. 2006 Feb;96(4):924-33. doi: 10.1111/j.1471-4159.2005.03595.x. Epub 2006 Jan 12. J Neurochem. 2006. PMID: 16412100 Free article.
99 results